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In vivo Skin Irritation Potential of a Castanea sativa (Chestnut) Leaf Extract,...

Almeida, IF; Valentão, P; Andrade, PB; Seabra, RM; Pereira, TM; Amaral, MH; Costa, PC; Bahia, MF

Topical application of natural antioxidants has proven to be effective in protecting the skin against ultraviolet-mediated oxidative damage and provides a straightforward way to strengthen the endogenous protection system. However, natural products can provoke skin adverse effects, such as allergic and irritant contact dermatitis. Skin irritation potential of Castanea sativa leaf ethanol:water (7:3) extract was...


Rosacea with extensive extrafacial lesions

Pereira, TM; Vieira, AP; Sousa-Basto, A

Rosacea is a very common skin disorder in the clinical practice that primarily affects the convex areas of the face. Extrafacial rosacea lesions have occasionally been described, but extensive involvement is exceptional. In the absence of its typical clinical or histological features, the diagnosis of extrafacial rosacea may be problematic. We describe an unusual case of rosacea with very exuberant extrafacial ...


In vivo Skin Irritation Potential of a Castanea sativa (Chestnut) Leaf Extract,...

Almeida, IF; Valentão, P; Andrade, PB; Seabra, RM; Pereira, TM; Amaral, MH; Costa, PC; Bahia, MF

Topical application of natural antioxidants has proven to be effective in protecting the skin against ultraviolet-mediated oxidative damage and provides a straightforward way to strengthen the endogenous protection system. However, natural products can provoke skin adverse effects, such as allergic and irritant contact dermatitis. Skin irritation potential of Castanea sativa leaf ethanol:water (7:3) extract was...

Data: 2008   |   Origem: Repositório Comum

Rosacea with extensive extrafacial lesions

Pereira, TM; Vieira, AP; Sousa-Basto, A

Rosacea is a very common skin disorder in the clinical practice that primarily affects the convex areas of the face. Extrafacial rosacea lesions have occasionally been described, but extensive involvement is exceptional. In the absence of its typical clinical or histological features, the diagnosis of extrafacial rosacea may be problematic. We describe an unusual case of rosacea with very exuberant extrafacial ...

Data: 2008   |   Origem: Repositório Comum

Allergic contact dermatitis from modified colophonium in wound dressings

Pereira, TM; Flour, M; Goossens, A

This study concerns a 69-year-old female patient with a longstanding history of venous ulcerations on both lower legs and multiple sensitivities, who developed eczematous lesions with the hydrocolloid dressing Combiderm (Convatec Ltd., a Bristol-Myers Squibb division, Ickenham, Middlesex, UK). Epicutaneous tests were positive to this dressing and to a modified colophonium derivative, i.e. glyceryl rosinate, how...

Data: 2007   |   Origem: Repositório Comum

Allergic contact dermatitis from modified colophonium in wound dressings

Pereira, TM; Flour, M; Goossens, A

This study concerns a 69-year-old female patient with a longstanding history of venous ulcerations on both lower legs and multiple sensitivities, who developed eczematous lesions with the hydrocolloid dressing Combiderm (Convatec Ltd., a Bristol-Myers Squibb division, Ickenham, Middlesex, UK). Epicutaneous tests were positive to this dressing and to a modified colophonium derivative, i.e. glyceryl rosinate, how...


Cyclosporin A treatment in severe childhood psoriasis

Pereira, TM; Vieira, AP; Fernandes, JC; Sousa-Basto, A

Though used occasionally, systemic therapies in severe childhood psoriasis have not been systematically investigated. Cyclosporin A (CysA) is effective in adults with severe psoriasis but there are no extensive data regarding the efficacy and safety of its use in childhood psoriasis. In this paper, we describe six children aged between 11 months and 13 years (average: 7.6 years) treated with CysA microemulsion ...


Cyclosporin A treatment in severe childhood psoriasis

Pereira, TM; Vieira, AP; Fernandes, JC; Sousa-Basto, A

Though used occasionally, systemic therapies in severe childhood psoriasis have not been systematically investigated. Cyclosporin A (CysA) is effective in adults with severe psoriasis but there are no extensive data regarding the efficacy and safety of its use in childhood psoriasis. In this paper, we describe six children aged between 11 months and 13 years (average: 7.6 years) treated with CysA microemulsion ...

Data: 2006   |   Origem: Repositório Comum

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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia