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Firms’ wage policies: New evidence from linked employer-employee data

The research on wage policies has been triggered by the interest in identifying whether labour market or institutional forces shape the wage settings inside firms. This paper draws on linked employer-employee data and uses a fuzzy c-means clustering analysis to identify typical wage policies of medium and large firms in Portugal. Empirical evidence suggests that firms are segmented into four clusters that can b...

Prevalence of the STK15 F31I polymorphism and its relationship with mammographi...

Several studies have identified the single nucleotide polymorphism STK15 F31I as a low-penetrance risk allele for breast cancer, but its prevalence and risk association in the Brazilian population have not been determined. The goal of this study was to identify the frequency of this polymorphism in the Brazilian setting. Considering the high degree of admixture of our population, it is of fundamental importance...

The APOE ε2 allele increases the risk of Earlier Age at onset in Machado-Joseph...

Background. Machado-Joseph disease (MJD) is an autosomal dominant neurodegenerative disorder of late onset, caused by a (CAG)n expansion at the ATXN3 gene (14q32.1). Variation in age-at-onset is partially explained by the size of the (CAG)n tract in expanded alleles. The remaining variation should be the product of other factors, namely modifier genes. The genotype at the APOE locus has been described as a poss...

Occupational therapy in spinocerebellar ataxia type 3: an open-label trial

Occupational therapy (OT) is a profession concerned with promoting health and well-being through occupation, by enabling handicapped people to participate in the activities of everyday life. OT is part of the clinical rehabilitation of progressive genetic neurodegenerative diseases such as spinocerebellar ataxias; however, its effects have never been determined in these diseases. Our aim was to investigate the ...

Antigenotoxic effects of quercetin, rutin and ursolic acid on HepG2 cells : eva...

In the present study, the chemoprotective effects of quercetin, rutin and ursolic acid on tert-butyl hydroperoxide (t-BHP)-induced DNA damage in a human hepatoma cell line (HepG2) were investigated by the comet assay. To determine whether protection was due to direct chemical interactions alone or to cellular-mediated responses three different types of treatments were used: simultaneous incubation of cells with...

Determinação de haplótipos no gene MJD1 em pacientes com Doença de Machado-Jose...

As manifestações depressivas na doença de Machado Joseph

Pesquisa de Ataxia Espinocerebral no Sul do Brasil - 158 novos casos de doença ...

Caracterização bioquímica da enzima quitotriosidase em plasma de pacientes com ...

Identificação e quantificação de expansões CAG nos genes de SCA1, SCA2 e SCA6