Atualmente, a escola assume um papel fundamental no desenvolvimento e na formação dos alunos. Por isso, o papel do professor emerge neste contexto como alguém que promove uma educação em todas as suas dimensões (pedagógica, socio afetiva, cultural e pessoal). A organização educativa onde se realizou a investigação assenta na sua missão que a exploração das potencialidades de cada um promove o sucesso educativo ...
Secondary immunodeficiences are associated with an increased incidence of infection and malignancy, as well with development ofautoimmune disease. Immune system function is altered by many conditions, such as aging, malnutrition and mycobacterial infections. However, the treatment of the primary condition often results in the improvement of the immune compromise. The authors present a case of cytomegalovirus en...
The fatty acid signature of sea lamprey Petromyzon marinus (L.) muscle was used as a tool to detect feeding strategies used during the parasitic marine trophic phase of the species. Adult sea lampreys were collected near the mouth of six Portuguese rivers (Minho, Lima, Douro, Vouga, Mondego and Tagus) and muscle fatty acid profile was characterized. The analysis of fatty acid composition of muscle neutral lipid...
Nanomaterials include all substances that contain nanoscale structures sized between 1 and 100 nm. At this size, the characteristics of materials change: their strength, conductivity, and reactivity, which differ substantially from macro- or micron- sized materials, shifting the rules of physics and chemistry to the sidelines. Although, the geological origin and the ubiquitous occurrence of nanoparticles in the...
The region of Beira Alta, Portugal distinguishes itself as a favorable area for apple growing that produces fruits with great economic importance. The polyphenoloxidase (EC 1.14.18.1, PPO) a copper-enzyme located in plastids, catalyzes the oxidation of phenols to quinones present in the vacuoles, generating brown coloration products. In general, the enzymatic browning occurs when phenolic compounds are released...
physicochemical properties are poorly known. In the case of metal nanoparticles, their dimension is often important, since their surface area increases as molecular size decreases, causing alterations in their magnetic and thermodynamic properties. Consequently, the influence they exert on life is an attractive topic of research in biochemical toxicology by the novelty of their behavior. Although titanium diox...
The determination of functional value of a particular food includes the discovery and characterization of their antioxidant properties, as its phenols contents, its ability to scavenge reactive oxygen species (ROS) or its biological activity to reverse oxidative stress markers, as triggered by vanadium (V) in eukaryotic models as S. cerevisiae, which exhibit high homology between their enzyme antioxidant respon...
Nanotechnology can be used to obtain materials at nanoscale (<100 nm) with new physicochemical and structural properties which depend on particle size and, probably, may trigger new biological effects. As Saccharomyces cerevisiae is an excellent model for study molecular and cell biology responses is growingly used in the toxicological evaluation of chemicals, such as heavy metals or nanoparticles of metal oxid...
The isoproturon (IPU), 3-(4-isopropylphenyl)-1,1-dimethylurea is an active component of several pesticides applied in autumn-winter crops which persist occasionally in the soil, aquifers and biological systems, at levels higher than established by directives of European Community. This phenylurea blocks photosynthesis, inhibiting chloroplasts electron chain at level of photosystem II. Therefore, the presence of...
A nanotecnologia liberta para o ambiente materiais com dimensão entre 1 e 100 nm, cujas propriedades magnéticas e termodinâmicas, maioritariamente condicionadas pela área superficial/dimensão molecular, determinam o tipo de interacção que estabelecem com as biomoléculas. A caracterização dos efeitos biológicos das nanopartículas constitui assim um tema de investigação aliciante em toxicologia bioquímica, pelo s...
Financiadores do RCAAP | |||||||
![]() |
![]() |
![]() |
![]() |
![]() |
![]() |