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Um olhar sobre a inclusão: conceções e práticas numa instituição educativa de n...

Pereira, Isabel

Atualmente, a escola assume um papel fundamental no desenvolvimento e na formação dos alunos. Por isso, o papel do professor emerge neste contexto como alguém que promove uma educação em todas as suas dimensões (pedagógica, socio afetiva, cultural e pessoal). A organização educativa onde se realizou a investigação assenta na sua missão que a exploração das potencialidades de cada um promove o sucesso educativo ...


Cytomegalovirus Encephalitis in an HIV-Negative Patient

Ferreira Santos, Carla; Serviço de Medicina Interna 2. Hospital de São Teotónio. Viseu. Portugal.

Secondary immunodeficiences are associated with an increased incidence of infection and malignancy, as well with development ofautoimmune disease. Immune system function is altered by many conditions, such as aging, malnutrition and mycobacterial infections. However, the treatment of the primary condition often results in the improvement of the immune compromise. The authors present a case of cytomegalovirus en...

Data: 2013   |   Origem: Acta Médica Portuguesa

Feeding strategy assessment through fatty acid profiles in muscles of adult sea...

Lança, Maria João; Machado, Maria; Ferreira, Rui; Alves-Pereira, Isabel; Quintella, Bernardo; Almeida, Pedro R.

The fatty acid signature of sea lamprey Petromyzon marinus (L.) muscle was used as a tool to detect feeding strategies used during the parasitic marine trophic phase of the species. Adult sea lampreys were collected near the mouth of six Portuguese rivers (Minho, Lima, Douro, Vouga, Mondego and Tagus) and muscle fatty acid profile was characterized. The analysis of fatty acid composition of muscle neutral lipid...


How does heat-shock affect the influence of titanium dioxide nanoparticles in g...

Capela-Pires, J; Ferreira, Rui; Alves-Pereira, Isabel

Nanomaterials include all substances that contain nanoscale structures sized between 1 and 100 nm. At this size, the characteristics of materials change: their strength, conductivity, and reactivity, which differ substantially from macro- or micron- sized materials, shifting the rules of physics and chemistry to the sidelines. Although, the geological origin and the ubiquitous occurrence of nanoparticles in the...


Enzyme activity profile of peroxidases and polifenoloxidases of Malus domestica...

Agostinho, J; Ferreira, Rui; Alves-Pereira, Isabel

The region of Beira Alta, Portugal distinguishes itself as a favorable area for apple growing that produces fruits with great economic importance. The polyphenoloxidase (EC 1.14.18.1, PPO) a copper-enzyme located in plastids, catalyzes the oxidation of phenols to quinones present in the vacuoles, generating brown coloration products. In general, the enzymatic browning occurs when phenolic compounds are released...


Titanium dioxide nanoparticles inhibits Saccharomyces cerevisiae BY4741 prolife...

Capela-Pires, J; Ferreira, Rui; Alves-Pereira, Isabel

physicochemical properties are poorly known. In the case of metal nanoparticles, their dimension is often important, since their surface area increases as molecular size decreases, causing alterations in their magnetic and thermodynamic properties. Consequently, the influence they exert on life is an attractive topic of research in biochemical toxicology by the novelty of their behavior. Although titanium diox...


Ability to scavenge free radicals by Malus domestica Borkh pulp reversed the st...

Agostinho, J; Ferreira, Rui; Alves-Pereira, Isabel

The determination of functional value of a particular food includes the discovery and characterization of their antioxidant properties, as its phenols contents, its ability to scavenge reactive oxygen species (ROS) or its biological activity to reverse oxidative stress markers, as triggered by vanadium (V) in eukaryotic models as S. cerevisiae, which exhibit high homology between their enzyme antioxidant respon...


Nanoparticles of titanium dioxide modulate the response to temperature by key e...

Capela-Pires, J; Ferreira, Rui; Alves-Pereira, Isabel

Nanotechnology can be used to obtain materials at nanoscale (<100 nm) with new physicochemical and structural properties which depend on particle size and, probably, may trigger new biological effects. As Saccharomyces cerevisiae is an excellent model for study molecular and cell biology responses is growingly used in the toxicological evaluation of chemicals, such as heavy metals or nanoparticles of metal oxid...


Induction of Saccharomyces cerevisiae UE-ME3 proliferation by isoproturon is in...

Candeias, Marta; Alves-Pereira, Isabel; Ferreira, Rui

The isoproturon (IPU), 3-(4-isopropylphenyl)-1,1-dimethylurea is an active component of several pesticides applied in autumn-winter crops which persist occasionally in the soil, aquifers and biological systems, at levels higher than established by directives of European Community. This phenylurea blocks photosynthesis, inhibiting chloroplasts electron chain at level of photosystem II. Therefore, the presence of...


Nanopartículas de dióxido de titânio revertem a repressao catabólica pela glico...

Capela-Pires, J; Ferreira, Rui; Alves-Pereira, Isabel

A nanotecnologia liberta para o ambiente materiais com dimensão entre 1 e 100 nm, cujas propriedades magnéticas e termodinâmicas, maioritariamente condicionadas pela área superficial/dimensão molecular, determinam o tipo de interacção que estabelecem com as biomoléculas. A caracterização dos efeitos biológicos das nanopartículas constitui assim um tema de investigação aliciante em toxicologia bioquímica, pelo s...


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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia