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CYP2C19*2 and prognosis after an acute coronary syndrome: Insights from a Portu...
Teixeira, R; Monteiro, P; Marques, G; Pego, J; Lourenço, M; Tavares, C; Reboredo, A; Monteiro, S; Gonçalves, F; Ferreira, MJ; Freitas, M; Ribeiro, GBACKGROUND: Clopidogrel requires oxidation dependent on the cytochrome P450 enzyme 2C19 (CYP2C19) to form its active metabolite. The importance of loss-of-function alleles (particularly CYP2C19*2, 681G>A) in poor platelet response to clopidogrel is well recognized. OBJECTIVE: To investigate the prevalence and prognostic impact of the CYP2C19*2 allele in a local acute coronary syndrome (ACS) population. METHOD...
Renal artery aneurysm: An endovascular treatment for a rare cause of hypertension
Moreira, N; Pêgo, M; Carvalheiro, V; Agostinho, A; Donato, P; Pego, J; Ferreira, MJ; Providência, LARenal artery aneurysms are a rare cause of secondary hypertension. Endovascular treatment with a polytetrafluoroethylene (PTFE)-coated stent can exclude aneurysms and treat hypertension. We report the case of a 23-year-old man with hypertension diagnosed three years earlier and in whom renal angiography revealed three aneurysms involving the right renal artery. A covered stent was implanted, resulting in succes...
Transvesical thoracoscopy: a natural orifice translumenal endoscopic approach f...
LIMA, E.; HENRIQUES‐COELHO, T.; ROLANDA, C.; PÊGO, J.M.; SILVA, D.; CARVALHO, J.L.; CORREIA‐PINTO, J.Surg Endosc. 2007 Jun;21(6):854-8. Epub 2007 May 4. Transvesical thoracoscopy: a natural orifice translumenal endoscopic approach for thoracic surgery. Lima E, Henriques-Coelho T, Rolanda C, Pêgo JM, Silva D, Carvalho JL, Correia-Pinto J. Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal. Abstract BACKGROUND: Recently there has been an increas...
Third‐generation nephrectomy by natural orifice transluminal endoscopic surgery
LIMA, E.; ROLANDA, C.; PÊGO, J.M.; HENRIQUES‐COELHO, T.; SILVA, D.; OSÓRIO, L.; MOREIRA, I.; CARVALHO, J.L.; CORREIA‐PINTO, J.Urol. 2007 Dec;178(6):2648-54. Epub 2007 Oct 22. Third-generation nephrectomy by natural orifice transluminal endoscopic surgery. Lima E, Rolanda C, Pêgo JM, Henriques-Coelho T, Silva D, Osório L, Moreira I, Carvalho JL, Correia-Pinto J. Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, Braga, Portugal. Abstract PURPOSE: Recently there has been increasing enthusiasm...
Transvesical endoscopic peritoneoscopy: a novel 5 mm port for intra‐abdominal s...
LIMA, E.; ROLANDA, C.; PEGO, J.M.; HENRIQUES‐COELHO, T.; SILVA, D.; CARVALHO, J.L.; CORREIA‐PINTO, J.J Urol. 2006 Aug;176(2):802-5. Transvesical endoscopic peritoneoscopy: a novel 5 mm port for intra-abdominal scarless surgery. Lima E, Rolanda C, Pêgo JM, Henriques-Coelho T, Silva D, Carvalho JL, Correia-Pinto J. Life and Health Sciences Research Institute, School of Health Sciences, University of Minho, Portugal. Abstract PURPOSE: Recently various groups reported successful attempts to perform intra-abdomi...
Morphological correlates of corticosteroid-induced changes in prefrontal cortex...
Cerqueira, J.; Pêgo, J.; Taipa, R.; Bessa, J.; Almeida, O.; Sousa, N.Imbalances in the corticosteroid milieu have been implicated in several neuropsychiatric disorders, including depression and schizophrenia. Prefrontal cortex (PFC) dysfunction is also a hallmark of these conditions, causing impairments in executive functions such as behavioral flexibility and working memory. Recent studies have suggested that the PFC might be influenced by corticosteroids released during stress...
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