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Gold nanoprobes for the detection of mutations associated with antibiotic resis...

Dissertação para obtenção do Grau de Mestre em Genética Molecular e Biomedicina ; Tuberculosis is still one of the leading human infectious diseases, with 8.7 million new cases reported in 2011 alone. Also, the increasing rate of multidrug-resistant tuberculosis (MDR-TB) and its treatment difficulties pose a serious public health threat especially in developing countries. Resistance to isoniazid and rifampicin...