Encontrados 17 documentos, a visualizar página 1 de 2

Análise ao valor acrescentado de um agente na carreira de um jogador e esclare...

Mestrado em Gestão do Desporto ; Nos últimos anos, a intervenção de agentes de jogadores, no futebol, tem-se feito sentir de forma cada vez mais intensa. Assim, se há 30 anos a figura do agente estava muito pouco presente nesta modalidade, com o agente a ter uma margem de intervenção reduzida, actualmente esta está presente no dia-a-dia do atleta. Hoje, o agente oferece ao jogador um acompanhamento diÃ...

Development of a flexible language for mission description for multi-robot miss...

AbstractThe work described in this paper is part of the development of a framework to support the joint execution of cooperative missions by a group of robotic vehicles, in a simulated, augmented or real environment. Such framework brings forward the need for formal languages in which to specify the group of vehicles that compose a team; the scenario in which they will operate; and the definition of the mission...

Heteroarylether 1,3-diarylureas in the thieno[3,2-d]pyrimidine series as VEGFR2...

Thieno[3,2-b]pyridine arylethers : synthesis and growth inhibitory activity on ...

Escoamentos Mistos em Colectores : Modelação matemática e algorítmos numéricos

As inundações urbanas são irremediavelmente e infelizmente uma realidade cada vez mais frequente nas nossas cidades. Caracterizam-se por serem fenómenos que conduzem a avultosos danos materiais e desembolso de elevadas quantias de dinheiro nas reparações mas sobretudo é necessário ter em conta os transtornos insupríveis e o sentimento de medo constante que provocam nas populações. Com o objectivo de potenciar e...

1-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as VEGFR2 tyrosine kin...

1-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as VEGFR2 inhibitors: ...

1-Aryl-3-[ 4-( thieno[3,2-d]pyrimidin-4-yloxy )phenyl]ureas as VEG FR2 inhibito...

A number of thienopyrimidines derivatives have shown potent VEGFR2 (Vascular Endothelium Growth Factor Receptor2) tyrosine kinase inhibition activity.[ll VEGF is a sun·ogate marker of angiogenesis that activates VEGFR2 in endothelial cells. Here we present the synthesis of new 1-aryl-3-[ 4-(thieno[3,2-d]pyrimidin-4- yloxy)phenyl]ureas from the aminodi(hetero)arylether 1, also prepared by us, which was reacted w...

1-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as VEGFR2 tyrosine kin...

A number of thienopyrimidines derivatives have shown potent vascular endothelial growth factor receptor 2 (VEGFR2) inhibition activity. Here, we present the synthesis of new 1-aryl-3-[4-(thieno[3,2-d) pyrimidin-4-yloxy)phenyl]ureas by promoting t he regioselective attack of the hydroxy group of the 4-aminophenol in the chlorine nucleophilic displacement on two 4-chlorinated thieno[3,2-d]pyrimidines, obtaining c...

Thieno[3,2-b]pyridine arylethers: synthesis and growth inhibitory activity on h...

Thienopyridine skeleton has been reported as havi ng inte resting biological activity, namely antitumorlll and antiangiogenic121 activities. Herein, we describe the synth esis of thienopyridine arylethers la-f in moderate to good yields by a copper-cata lyzed C- 0 coupling, using N,N-dimethylglycine as a ligand, of the 7-bromothieno[3,2-b]pyridine, also prepared with substituted phenols (see scheme).