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Chemical study and biological activity evaluation of two Azorean Macroalgae: Ul...
Silva, Madalena; Vieira, Luís M.; Almeida, Ana Paula; Silva, Artur M. S.; Seca, Ana M. L.; Barreto, Maria do Carmo; Neto, Ana I.; Pedro, MadalenaCopyright: © 2013 Silva M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credite. ; The green macroalga Ulva rigida C. Agardh (Chlorophyta) and the red macroalga Gelidium microdon Kützing (Rhodophyta), collected from the Azore...
3-bromopyruvate, butyrate, monocarboxylate transporters, warburg effect
Queirós, Odília; Preto, Ana; Pacheco, António; Pinheiro, Céline; Silva, João Azevedo; Moreira, Roxana; Pedro, Madalena; Ko, Young; Pedersen, PeterThe authors are deeply grateful to Professor André Goffeau (Université Catholique de Louvain-la-Neuve, Belgium) for his contagious vision, valuable discussions at the Conference on 3-BP held in Brussels, 29 October–2 November, 2011 and critical reviewing of the manuscript. The authors also thank Dr. Rita Reis for her technical support in microscopy and image analysis. ; Most malignant tumors exhibit theWarburg...
Psoralen analogues : synthesis, inhibitory activity of growth of human tumor ce...
Oliveira, Ana M. A. G.; Campos, Ana M. F. Oliveira; Raposo, M. Manuela M.; Machado, António E. H.; Puapairoj, Prapawadee; Pedro, MadalenaEight psoralens have been evaluated for their ability to inhibit the in vitro growth of three human turner cell lines representing different tumor types, MCF-7 (breast cancer), NCI-14460 (non-small cell lung cancer) and SF-268 (CNS cancer). The synthesis of four new psoralens (benzofur-ocournarins) is presented as well as the results of the ab initio calculations to find the parameters that relate the structure...
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