A PDE integration algorithm that associates a Method of Lines (MOL) strategy based on finite differences or high resolution space discretizations, with a collocation strategy based on increasing level one or two-dimensional dyadic grids is presented. It reveals potential either as a grid generation procedure for predefined steep localised functions, and as an integration scheme for moving steep gradient PDE pro...
A PDE integration algorithm that associates a Method of Lines (MOL) strategy based on finite differences or high resolution space discretizations, with a collocation strategy based on increasing level one or two-dimensional dyadic grids is presented. It reveals potential either as a grid generation procedure for predefined steep localised functions, and as an integration scheme for moving steep gradient PDE pro...
An integration algorithm that conjugates a Method of Lines (MOL) strategy based on finite differences space discretizations, with a collocation strategy based on increasing level dyadic grids is presented. It reveals potential either as a grid generation procedure and a Partial Differential Equation(PDE) integration scheme. It copes satisfactorily with a example characterized by a steep travelling wave and a ex...
A coupled model of concentration polarization and membrane transport is used to study the crossflow ultrafiltration of PEG-3400 solutions. For the intramembrane transport, the model incorporates the binary friction model (BFM) derived by Kerkhof [4] and that is a modification of the Maxwell-Stefan-Lightfoot equation. Good agreement between model predictions and experimental data (apparent rejections and pressur...
In this paper two adaptive algorithms are presented for the solution of systems of evolutive one-dimensional Partial Differential/ AIgebraic Equations (PDAEs). A spatial discretization based on finite difference approximations on arbitrarily spaced grids: transforms the original problem in a set of Ordinary Differential Equations (ODEs), solved via an implicit integrator package (DASSL). The temporal integratio...
In this paper two adaptive algorithms are presented for the solution of systems of evolutive one-dimensional Partial Differential/ Algebraic Equations (PDAEs). The temporal integration is coupled with a spatial adapting strategy. The identification of the spatial subdomains. where a regridding technique is introduced, is done through the comparison of the solutions computed with two fixed grids of different siz...
The dissolution of powder drugs, besides being a topic of utmost importance, especially for the sparingly soluble ones, is far from being well-explained. The purpose of the present study is, on the one hand, to obtain experimental dissolution profiles and, on the other hand, to analyze and process the data for dissolution modeling. Three different size fractions of a widely used sparingly soluble drug - ibuprof...
The dissolution of powder drugs, besides being a topic of utmost importance, especially for the sparingly soluble ones, is far from being well-explained. The purpose of the present study is, on the one hand, to obtain experimental dissolution profiles and, on the other hand, to analyze and process the data for dissolution modeling. Three different size fractions of a widely used sparingly soluble drugsibuprofen...
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