Dissertação para obtenção do Grau de Mestre em Engenharia Biomédica ; A dissecção de cadáveres, fundamental para estudo anatómico, só é recomendável mediante da conservação cadavérica prévia de longo prazo, recorrendo a técnicas avançadas de embalsamamento. O embalsamamento é um processo químico que tem como objectivo impedir ou retardar o aparecimento e progressão dos fenómenos cadavérico-destrutivos, conduce...
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The BLEVE is a kind of technological accident with a major impact on society due to the possibility of causing death and disability on people as well as property damage. This kind of accident is the result of the production of a pressure wave generated by the release of stored energy, of the heat flux generated by a fireball and the projection of fragments generated by the rupture of the shell and materials fro...
In the present work, to maintain a suitable blood level of vinpocetine (VP) for a long period of time, VP-cyclodextrin-tartaric acid multicomponent complexes were prepared and formulated in hydroxypropylmethylcellulose matrix tablets. In vitro and in vivo performances of these formulations were investigated over a VP immediate release dosage form. Solubility studies were performed to evaluate the drug pH solubi...
In the present work, to maintain a suitable blood level of vinpocetine (VP) for a long period of time, VP-cyclodextrin-tartaric acid multicomponent complexes were prepared and formulated in hydroxypropylmethylcellulose matrix tablets. In vitro and in vivo performances of these formulations were investigated over a VP immediate release dosage form. Solubility studies were performed to evaluate the drug pH solubi...
We study and compare preconditioners available for network interior point methods. We derive upper bounds for the condition number of the preconditioned matrices used in the solution of systems of linear equations defining the algorithm search directions. The preconditioners are tested using PDNET, a state-of-the-art interior point code for the minimum cost network flow problem. A computational comparison using...
Two surgical models of intestinal transplantation in the rat are described. One is the implantation of fetal and newborn intestine as free grafts into the omentum of adult recipients, the other the adult intestine transplantation as an accessory graft using vascular anastomoses. A hundred and sixteen small-bowel transplantations were done; 36 of which were fetal intestine (group I), 40 of newborn intestine (gro...
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