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Effects of acute ischaemia induced by atrial pacing on coronary blood flow in d...

Five anaesthetized open chested dogs were studied by measuring left anterior descending (LAD) coronary blood flow, at rest, after atrial pacing and after Isoprenaline infusion. The LAD was then stenosed in order to reduce the hyperaemic response and then the study was repeated. During the control situation LAD flow was shown to increase with the increase in heart rate. Although the partial occlusion did not dro...