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The Bactericidal Activity of Carbon Monoxide-Releasing Molecules against Helico...
Tavares, A.F.; Parente, M.R.; Justino, M.; Oleastro, M.; Nobre, L.S.; Saraiva, L.M.Helicobacter pylori is a pathogen that establishes long life infections responsible for chronic gastric ulcer diseases and a proved risk factor for gastric carcinoma. The therapeutic properties of carbon-monoxide releasing molecules (CORMs) led us to investigate their effect on H. pylori. We show that H. pylori 26695 is susceptible to two widely used CORMs, namely CORM-2 and CORM-3. Also, several H. pylori clin...
The influence of muscles activation on the dynamical behaviour of the tympano-o...
Gentil, F; Parente, M; Martins, P; Garbe, C; Paço, J; Ferreira, AJ; Tavares, JM; Jorge, RNThe human ear is a complex biomechanical system and is divided into three parts: outer, middle and inner ear. The middle ear is formed by ossicles (malleus, incus and stapes), ligaments, muscles and tendons, which transfers sound vibrations from the eardrum to the inner ear, linking with mastoid and Eustachian tube. In this work, a finite element modelling of the tympano-ossicular system of the middle ear was d...
Ciprofloxacin susceptibility patterns of planktonic and sessile S. aureus, E. c...
Parente, M.; Machado, Idalina; Pereira, M. O.Several aspects of human infections within a clinical arena are related to biofilm development. Various surfaces, like indwelling devices and medical equipments, are prone to biofilm formation, causing subsequent pathogenesis. The application of antimicrobial agents is one of the main strategies to eradicate biofilms. However, the action of antibiotics could be inefficient duo to the high tolerance of biofilmes...
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