Atopic eczema is a common inflammatory skin disease, affecting up to 20% of children and 3% of adults in industrialized countries. Most cases of atopic eczema are mild to moderate and will be adequately managed with topical therapy. Persistent or severe cases may require periods of systemic treatment, which can be broadly grouped into conventional and biologic agents. Conventional systemic agents are associated...
Basal cell carcinomas arising on the genitalia and over 5 cm in size are exceedingly rare. We report a case of a 60-year-old man with a lesion on the scrotum which had been slowly enlarging over the previous year. On examination he had an erythematous plaque 6.0x5.0cm in size with a pedunculated nodule. We performed an incisional biopsy. The histopathological diagnosis was basal cell carcinoma. The tumor was su...
Objectives: To determine clinical and histopathological differences between melanoma associated with nevus (MAN) and de novo melanoma (MN). Methods: Retrospective study of all cases of cutaneous melanoma diagnosed between 2001 and 2009 in Centro de Dermatologia Médico-Cirúrgica de Lisboa. Results: Of the 397 melanomas included, 52.6% were of feminine sex and 47.4% of the masculine. Of these melano- mas only 9....
Introduction: Lichen sclerosus (LS) is a chronic idiopathic inflammatory disease that preferentially affects the anogenital region and postmenopausal Caucasian women. Aims: Retrospective characterization of patients with vulvar LS diagnosed and treated at our Department (Vulvar Pathology Consultation), between 1986 and 2004. Material and Methods: A total of 208 Caucasians women were included in the study. We co...
Introduction: Malignant melanoma may present a great variety of histopathological patterns. Besides the classic forms of melanoma, there are a number of variants that have been described, such as polypoid, verrucous, desmoplastic, myxoid, chondroid, balloon-cell, rhabdoid, animal-type, amelanotic, spitzoid, nevoid. The aim of this study was to characterize the rare histopathologic variants of malignant melanoma...
Introduction: TNF-α plays an important role in immune defense against Mycobacterium tuberculosis and, as such, the risk of reactivation of latent tuberculosis increases with the TNF-blocking agents. Aims: To determine the prevalence of latent tuberculosis in psoriasis patients undergoing TNF-blocking agents, between 2006 and 2009. Assess the established therapy and their complications. Materials and methods: Re...
Introdução: As úlceras crónicas de perna (UCP) são motivos frequentes de prescrição antibiótica ge- ralmente indiscriminada, facto que tem contribuído para o aumento das resistências bacterianas. Objetivo: Cara- terização retrospetiva da flora microbiana presente nos exsudados de UCP sobre-infetadas e o respetivo perfil de suscetibilidade antibiótica, em doentes internados entre 2007 e 2011 (5 anos). Material e...
Spontaneous ileopsoas hematoma is a rare and potentially lethal complication of liver cirrhosis, with exceptional mention in medical literature. In this article we present a clinical case diagnosed in a patient with alcoholic liver cirrhosis. ; O hematoma espontâneo do ileopsoas é uma complicação rara e potencialmente fatal da cirrose hepática, excepcionalmente mencionada na literatura. Descrevemos neste artig...
The authorsacknowledge Karl Storz, Richard Wolf and Covidien for their support with equipment. ; What's known on the subject? and What does the study add? Until now, the transvaginal approach has been the only method of removing larger specimens from the abdominal cavity using natural orifi ce transluminal endoscopic surgery. There has been no means of extracting larger specimens in men and the means are restr...
Os idosos pertencem a um grupo populacional que necessita de uma atenção especial por parte dos profissionais de saúde devido à elevada incidência de doenças crónicas e incapacitantes e, consequentemente, à prescrição mais extensa nesta subpopulação, aumentando o risco da ocorrência de problemas relacionados com os medicamentos. Um desses problemas relatados frequentemente na literatura é a utilização de medica...
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