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Corneal biomechanical properties in different ocular conditions and new measure...

Garcia-Porta, Nery; Fernandes, Paulo Rodrigues; Queirós, A.; Borges, José Salgado; Parafita, Manuel A.; González-Méijome, José Manuel

Several refractive and therapeutic treatments as well as several ocular or systemic diseases might induce changes in the mechanical resistance of the cornea. Furthermore, intraocular pressure measurement, one of the most used clinical tools, is also highly dependent on this characteristic. Corneal biomechanical properties can be measured now in the clinical setting with different instruments. In the present wor...


Long-term changes in corneal structure and tear inflammatory mediators after or...

González-Pérez, Javier; Villa-Collar, César; González-Méijome, José Manuel; Garcia-Porta, Nery; Parafita, Manuel A.

PURPOSE: To monitor changes in corneal structure and level of inflammatory mediators in tears of myopic patients following orthokeratology (OK) and laser in situ keratomileusis (LASIK). METHODS: Sixty-two myopic subjects were analyzed in this prospective study. Thirty-two had worn Paragon CRT contact lenses and 30 underwent standard LASIK. Thirty-two control subjects were also recruited. Pachometry and corneal...


Tear film inflammatory mediators during continuous wear of contact lenses and c...

González-Pérez, Javier; Villa-Collar, César; Sobrino Moreiras, Tomás; Lema Gesto, Isabel; González-Méijome, José Manuel; Rodríguez Ares, María T.

OBJECTIVES: To study changes in tear film inflammatory mediators following continuous wear of silicone-hydrogel lenses and corneal refractive therapy with reverse geometry contact lenses. DESIGN: A prospective, case-control study. METHODS: Twenty-eight subjects had worn silicone-hydrogel lenses on a 30-night continuous wear basis. Thirty-two subjects had worn corneal refractive therapy lenses on an overnight ...


Topographic paracentral corneal thickness with pentacam and orbscan : effect of...

González-Pérez, Javier; González-Méijome, José Manuel; Rodríguez Ares, María T.; Parafita, Manuel A.

Purpose: To evaluate the effect of an acoustic factor (AF) on the comparison of central corneal thickness (CCT) and peripheral corneal thickness (PCT) measurements with Orbscan II and Pentacam. Methods: The CCT and PCT at 1, 2, and 3 radial distances from the corneal apex were measured using Orbscan II and Pentacam in 22 right eyes of 22 healthy adults (7 men, 15 women). Three measures were obtained from each 1...


Analysis of surface mechanical properties of unworn and worn silicone hydrogel ...

González-Méijome, José Manuel; Almeida, José B.; Parafita, Manuel A.


Surface AFM microscopy of unworn and worn samples of silicone hydrogel contact ...

González-Méijome, José Manuel; López-Alemany, António; Almeida, José B.; Parafita, Manuel A.

Abstract: Purpose. To evaluate the qualitative and quantitative topographic changes in the surface of worn contact lenses (CLs) of different materials using atomic force microscopy (AFM). Methods. The topography of five different CL materials was evaluated withAFM over a surface of 25 lm2 according to previously published experimental setup. Average roughness (Ra) and root mean square (Rms) values were obtained...


A pilot study on the influence of biomechanical properties of the cornea on sho...

González-Méijome, José Manuel; Villa-Collar, César; Queirós, A.; Jorge, Jorge; Parafita, Manuel A.

The authors state that they do not have any proprietary interest in the products named in this article. ; To study the short-term corneal response to corneal refractive therapy for myopia and correlate it with corneal biomechanical properties as measured with the ocular response analyzer. METHODS: Eight eyes from 8 young subjects were fitted with a reverse geometry contact lens, attempting a myopic correction ...


Correlations between corneal biomechanical properties measured with the ocular ...

Jorge, Jorge; González-Méijome, José Manuel; Queirós, A.; Fernandes, Paulo Rodrigues; Parafita, Manuel A.

Purpose: To investigate the biomechanical properties of the normal cornea, and correlate them with central and peripheral corneal thickness and age. Methods: Seventy-six right eyes of volunteers were measured with Ocular Response Analyzer (ORA), ICare rebound tonometry and an ultrasound pachymeter at corneal center and at 4 mm from corneal center in the nasal and temporal directions. Results: ICare readings w...


Accuracy and repeatability of a new portable ultrasound pachymeter

Queirós, A.; González-Méijome, José Manuel; Fernandes, Paulo Rodrigues; Jorge, Jorge; Almeida, José B.; Parafita, Manuel A.

To assess the accuracy and repeatability of central corneal thickness (CCT) measurements taken with a new portable ultrasound (US) pachymeter. Methods: Central thickness measurements were taken with a portable pachymeter (SP-100 Handy;Tomey, Nagoya, Japan) and a conventional US pachymeter (Nidek UP-1000; Nidek Technologies, Gamagori, Japan) from 57 right corneas of 57 young adults (19 males, 38 females) aged 18...


Symptoms in a population of contact lens and noncontact lens wearers under diff...

González-Méijome, José Manuel; Parafita, Manuel A.; Yebra-Pimentel Vilar, Eva; Almeida, José B.

None of the authors has a commercial or financial interest in the instruments or materials used in the study. The authors wish to thank the assistance of AP Almeida, AP Costa, A, Fernandes, A Teixeira, C Marques, C Pinho and J Matos for their assistance in data acquisition, and Dr. Ana Costa from the program of Support to the Edition of Scientific Papers at the University of Minho for help with English editing ...


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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia