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Thermal and hydrolytic degradation of electrospun fish gelatin membranes
Correia, D.M.; Padrão, J; Rodrigues, L. R.; Dourado, F.; Lanceros-Mendez, S.; Sencadas, V.The thermal and hydrolytic degradation of electrospun gelatin membranes cross-linked with glutaraldehyde in vapor phase has been studied. In vitro degradation of gelatin membranes was evaluated in phosphate buffer saline solution at 37 ºC. After 15 days under these conditions, a weight loss of 68 % was observed, attributed to solvation and depolymerization of the main polymeric chains. Thermal degradation kinet...
PHB-PEO electrospun fiber membranes containing chlorhexidine for drug delivery ...
Fernandes, J. G.; Correia, D. M.; Botelho, G.; Padrão, J.; Ribeiro, C.; Lanceros-Mendez, S.; Sencadas, V.Fiber meshes of poly(hydroxybutyrate) (PHB) and poly(hydroxybutyrate)/ poly(ethylene oxide) (PHB/PEO) with different concentrations of chlorhexidine (CHX) were prepared by electrospinning, for assessment as a polymer based drug delivery system. The electrospun fibers were characterized at morphological, molecular and mechanical levels. The bactericidal potential of PHB and PHB/PEO electrospun fibers with and wi...
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