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Genome-wide identification of genes involved in the positive and negative regul...

Sousa, Marlene; Duarte, Ana Marta Gomes; Fernandes, Tânia Alícia Ribeiro; Chaves, S. R.; Pacheco, Andreia; Leão, Cecília; Côrte-Real, Manuela

Background: Acetic acid is mostly known as a toxic by-product of alcoholic fermentation carried out by Saccharomyces cerevisiae, which it frequently impairs. The more recent finding that acetic acid triggers apoptotic programmed cell death (PCD) in yeast sparked an interest to develop strategies to modulate this process, to improve several biotechnological applications, but also for biomedical research. Indeed,...


C2-phytoceramide perturbs lipid rafts and cell integrity in Saccharomyces cerev...

Pacheco, Andreia; Azevedo, Flávio; Rego, António; Santos, Júlia; Chaves, S. R.; Côrte-Real, Manuela; Sousa, Maria João

Specific ceramides are key regulators of cell fate, and extensive studies aimed to develop therapies based on ceramide-induced cell death. However, the mechanisms regulating ceramide cytotoxicity are not yet fully elucidated. Since ceramides also regulate growth and stress responses in yeast, we studied how different exogenous ceramides affect yeast cells. C2-phytoceramide, a soluble form of phytoceramides, the...


Baker’s yeasts for use in frozen-dough technology : sugar utilization in freeze...

Pacheco, Andreia

Tese de doutoramento em Ciências (ramo de conhecimento em Biologia) ; Bread is a central dietary item in most countries of the world. Currently, frozen dough technology is extensively used in the baking industry to supply oven-fresh bakery products to consumers and to improve labor conditions for bakers. Since freeze–thaw stress affects the viability and activity of yeast cells, one serious disadvantage of thi...


Estilos de vida, qualidade de vida pessoal, motivação e sucesso académico: o ca...

Pacheco, Andreia Sofia Ramos

Dissertação mest., Psicologia, Universidade do Algarve, 2008


Molecular and biochemical characterization of glucose transport in Torulaspora ...

Pacheco, Andreia; Almeida, M. J.; Hernandez-Lopez, Maria José; Prieto, J. A.; Randez-Gil, Francisca; Sousa, Maria João; Leão, Cecília

Apresentação efectuada no "XIV Congresso Nacional de Bioquímica", em Vilamoura, Portugal, em Dezembro de 2004.


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia