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The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloi...
HIRSCH‐REINSHAGEN, V.; MAIA, L.F.; BURGESS, B.L.; BLAIN, J.F.; NAUS, K.E.; MCISAAC, S.A.; PARKINSON, P.F.; CHAN, J.Y.; TANSLEY, G.H.; HAYDEN, M.R.J Biol Chem. 2005 Dec 30;280(52):43243-56. Epub 2005 Oct 5. The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease. Hirsch-Reinshagen V, Maia LF, Burgess BL, Blain JF, Naus KE, McIsaac SA, Parkinson PF, Chan JY, Tansley GH, Hayden MR, Poirier J, Van Nostrand W, Wellington CL. Department of Pathology and Laboratory Medicine, Univers...
Transitory increased blood pressure after upper airway surgery for snoring and ...
Araújo,M.T.M.; Ouayoun,M.; Poirier,J.M.; Bayle,M.M.; Vasquez,E.C.; Fleury,B.A transitory increase in blood pressure (BP) is observed following upper airway surgery for obstructive sleep apnea syndrome but the mechanisms implicated are not yet well understood. The objective of the present study was to evaluate changes in BP and heart rate (HR) and putative factors after uvulopalatopharyngoplasty and septoplasty in normotensive snorers. Patients (N = 10) were instrumented for 24-h ambula...
Trinucleotide repeats in 202 families with ataxia: a small expanded (CAG)n alle...
Silveira, I; Miranda, C; Guimarães, L; Moreira, MC; Alonso, I; Mendonça, P; Ferro, A; Pinto-Basto, J; Coelho, J; Ferreirinha, F; Poirier, J; Vale, JBACKGROUND: Ten neurodegenerative disorders characterized by spinocerebellar ataxia (SCA) are known to be caused by trinucleotide repeat (TNR) expansions. However, in some instances the molecular diagnosis is considered indeterminate because of the overlap between normal and affected allele ranges. In addition, the mechanism that generates expanded alleles is not completely understood. OBJECTIVE: To examine the...
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