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Bacterial cellulose : long-term biocompatibility studies

Pértile, Renata Aparecida Nedel; Moreira, Susana; Costa, Rui M. Gil da; Correia, Alexandra; Guardão, Luísa; Gartner, Fátima; Vilanova, Manuel

The bacterial cellulose (BC) secreted by G. xylinus is a network of pure cellulose nanofibers, which has high crystallinity, wettability and mechanical strength. These characteristics make BC an excellent material for tissue engineering constructs, noteworthy for artificial vascular grafts. In this work, the in vivo biocompatibility of BC membranes produced by two G. xylinus strains was analyzed through histolo...


Bacterial cellulose modified using recombinant proteins to improve neuronal and...

Pértile, Renata Aparecida Nedel; Moreira, Susana; Andrade, Fábia K.; Domingues, Lucília; Gama, F. M.

A wide variety of biomaterials and bioactive molecules have been applied as scaffolds in neuronal tissue engineering. However, creating devices that enhance the regeneration of nervous system injuries is still a challenge, due the difficulty in providing an appropriate environment for cell growth and differentiation and active stimulation of nerve regeneration. In recent years, bacterial cellulose (BC) has em...


Bacterial cellulose : studies on biocompatibility, surface modification and int...

Pértile, Renata Aparecida Nedel

Tese doutoramento em Engenharia Biomédica ; A wide variety of biomaterials and bioactive molecules have been applied in tissue engineering as scaffolds in order to provide an appropriate environment to the growth and differentiation of cells. However, creating devices for biological substitutes that enhance the regeneration of neural tissues is still a challenge, because of the difficulty in providing an activ...


Surface modification of bacterial cellulose by nitrogen-containing plasma for i...

Pértile, Renata Aparecida Nedel; Andrade, Fábia K.; Alves Junior, Clodomiro; Gama, F. M.

Bacterial cellulose (BC) membranes were modified with nitrogen plasma in order to enhance cell affinity. The surface properties of the untreated and plasma modified BC (BCP) were analyzed through contact angle measurements, X-ray photoelectron spectroscopy (XPS) and scanning electron microscopy (SEM). The effect of the plasma treatment on the adhesion of microvascular (HMEC-1), neuroblast (N1E-115) and fibrobla...


Bacterial cellulose : production and applications

Dourado, Fernando; Silva, João P.; Karine, Fábia; Pértile, Renata Aparecida Nedel; Padrão, Jorge; Gonçalves, S.; Machado, João; Leitão, Alexandre F.


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia