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A first new look into the interaction of Staphylococcus epidermidis biofilm-rel...
França, Ângela; Pérez-Cabezas, B.; Carvalhais, V.; Freitas, Ana I.; Pier, G.; Vilanova, Manuel; Cerca, NunoThe widespread application of indwelling medical devices in the clinical setting, together with the remarkable ability of the commensal Staphylococcus epidermidis to adhere to these surfaces and form biofilms, has given to this bacterium the recognition of being a leading causative agent of nosocomial infections. Biofilms lifecycle is currently divided into 4 main steps: initial adhesion, accumulation, maturati...
Genomic characterization of the Staphylococcus epidermidis-specific bacteriopha...
Melo, Luís D. R.; Oliveira, F.; Sillankorva, Sanna; Pérez-Cabezas, B.; Ackermann, H. W.; Kropinski, Andrew M.; Vilanova, Manuel; Azeredo, JoanaStaphylococcus epidermidis is one of the most frequent causative agents of nosocomial infections, predominantly in patients with indwelling medical devices. This microrganism may form biofilms which are microbial structures very tolerant to the host immune defenses and to antibiotherapy. Therefore, studies are needed in order to develop effective methods for biofilm control. Currently, bacteriophages (phages) a...
Medium supplementation with magnesium prevented the induction of dormancy in bi...
Pérez-Cabezas, B.; Oliveira, C.; Carvalhais, V.; Freitas, Ana I.; Oliveira, F.; Cerca, Nuno; Vilanova, ManuelStaphylococcus epidermidis is a commensal bacterium that colonizes the skin and mucous membranes, being the most prevalent staphylococcal species found in humans. However, S. epidermidis has the ability of colonize indwelling medical devices establishing biofilms, which makes this bacteria a common cause of bacteraemia particularly in immunocompromised individuals and neonates [1][2]. The presence of high amoun...
Staphylococcus epidermidis biofilm lifecycle and its virulence: from plantkonic...
França, Ângela; Freitas, Ana I.; Carvalhais, V.; Pérez-Cabezas, B.; Correia, A.; Cywes-Bentley, C.; Maira-Litrán, Tomas; Vilanova, M.; Pier, Gerald B.
Efficacy studies of phage phiIBB-Sep1 against S. epidermidis cells under differ...
Melo, Luís D. R.; Oliveira, F.; Sillankorva, Sanna; Pérez-Cabezas, B.; Vilanova, Manuel; Azeredo, Joana; Cerca, NunoStaphylococcus epidermidis has recently become known as a usual cause of nosocomial infections, predominantly in patients with indwelling medical devices. Although, S. epidermidis infections only rarely develop into life-threatening diseases, they are very frequent and difficult to treat due to the ability of this bacterium to adhere to the surfaces of indwelling medical devices and form biofilms. When S. epide...
The proportions of dormant bacteria within Staphylococcus epidermidis biofilms ...
Cerca, Filipe; Pérez-Cabezas, B.; França, Ângela; Cerca, Nuno; Vilanova, Manuel
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