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Phototherapy in Childhood: a 17-Year Retrospective Study Regarding Effectivenes...

Brasileiro, A; Campos, S; Páris, F; Fidalgo, A; Apetato, M

Introduction: Skin diseases in paediatric age are often distressing conditions with significant impact in children’s psychosocial development. Additionally, systemic therapeutic options are often limited in childhood, due to its potential toxicity in this vulnerable group. Phototherapy is therefore an endorsed option for photo-responsive dermatological conditions. Objective and Methods:This observational retr...


Fototerapia como Adjuvante da Terapêutica Biológica na Psoríase

Cabete, J; Serrão, V; Lestre, S; Páris, F; Apetato, M

Introdução: A associação terapêutica é uma estratégia frequentemente usada no tratamento da psoríase. Contudo, a associação de fármacos biológicos com terapêuticas convencionais, e em particular com fototerapia, tem sido pouco explorada. Objectivo: Caracterizar a eficácia e a segurança da associação fototerapia-terapêutica biológica no tratamento da psoríase. Métodos: Foram analisados retrospectivamente os proc...


Intravenous Immunoglobulin for the Treatment of Quetiapin-Induced Bullous Pemph...

Cabete, J; Santos, G; Páris, F; Serrão, V; Fidalgo, A

The authors present the case of a 48-year-old woman with HIV-­associated dementia treated with antiretroviral therapy and psychoactive drugs, to whom bullous pemphigoid(BP) was diagnosed. Given incomplete response to corticotherapy, and azathioprine-­induced bicytopenia,intravenous immunoglobulin(IVIG) was initiated. Despite transient disease control, recurrent flares suggested a persistent triggering factor. S...


Effect of inhibitory avoidance training on [3H]-glutamate binding in the hippoc...

Schröder,N.; de-Paris,F.; Roesler,R.; Medina,J.H.; Souza,D.O.; Izquierdo,I.

Glutamate receptors have been implicated in memory formation. The aim of the present study was to determine the effect of inhibitory avoidance training on specific [3H]-glutamate binding to membranes obtained from the hippocampus or parietal cortex of rats. Adult male Wistar rats were trained (0.5-mA footshock) in a step-down inhibitory avoidance task and were sacrificed 0, 5, 15 or 60 min after training. Hippo...

Data: 2000   |   Origem: OASIS br

Infusions of AP5 into the basolateral amygdala impair the formation, but not th...

Roesler,R.; Vianna,M.R.M.; de-Paris,F.; Quevedo,J.; Walz,R.; Bianchin,M.

We evaluated the effects of infusions of the NMDA receptor antagonist D,L-2-amino-5-phosphonopentanoic acid (AP5) into the basolateral nucleus of the amygdala (BLA) on the formation and expression of memory for inhibitory avoidance. Adult male Wistar rats (215-300 g) were implanted under thionembutal anesthesia (30 mg/kg, ip) with 9.0-mm guide cannulae aimed 1.0 mm above the BLA. Bilateral infusions of AP5 (5.0...

Data: 2000   |   Origem: OASIS br

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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia