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Importance of xeroderma pigmentosum group D polymorphisms in susceptibility to ...
Costa, Sandra Maria Araújo da; Pinto, Daniela; Pereira, Deolinda; Vasconcelos, André; Lopes, Carlos Afonso; Osório, Teresa; Lopes, Carlos; Medeiros, RuiThe purpose of this study was to evaluate the role of XPD genotypes as genetic indicator of susceptibility to ovarian cancer. We have used a case–control study. We analysed DNA samples from 141 ovarian cancer patients and 202 control subjects, for three XPD polymorphisms using PCR-RFLP. We observed that Asn312Asn XPD genotype carriers have increased susceptibility of ovarian cancer (ORZ2.46 95% CI 1.20–5.06; PZ...
Data: 2007
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Origem: RepositóriUM - Universidade do Minho
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