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Apoptosis as a prognostic marker in prediction of renal injury, after acute ble...

Cruz, R.; Vala, H.; Machado, A.; Venâncio, C.; Mesquita, J.; Silva, A.; Ortiz, A. L.; Ferreira, D.

Objectives: The aim of this study is to identify and quantify apoptosis in renal tissue, using a biochemical marker (TUNEL) in a pig haemorrhagic model, after intravascular volume replacement with Ringer's lactate RL) or Hydroxyethylstarch (HES) 130/0.4) solutions. Methods: 18 Large White pigs underwent total intravenous anaesthesia (TIVA) with propofol and remifentanil. 25 ml/kg of arterial blood were removed ...


Evaluation and characterization of intestinal oedema in pigs

Ortiz, A. L.; Vala, Helena; Silva, A.; Venâncio, C.; Garcia, C.; V, D.

Introduction When characterizing small intestine early lesions in studies concerning intestinal hypoperfusion in pigs, authors faced a significant difficulty when trying to standard the oedema grading to allow an accurate comparison between groups. Therefore, specific alterations were assumed to characterize grade1 (G1), grade2 (G2) and grade3 (G3) oedema. Material and Methods Eighteen Large White pigs underwen...


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia