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Polimorfismos nos genes TP53, 53BP1 e ATM: Susceptibilidade para cancro do colo...

Cell cycle progresses without interruptions. However, when DNA damage occurs, namely double strand breaks, cells are able to stops transiently her proliferation. In response to this threat, eucariotic cells develop mechanisms, which detect this damage DNA. Thereby generally this DNA can be repaired. The kinase protein, pATM, carries out this response. Upon identification of the damage DNA, pATM is activated a...