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6174: um problema com números de quatro algarismos
Oliveira, Paulo E.; CMUC, Departamento de Matemática Universidade de CoimbraAborda-se um problema clássico da chamada matemática recreativa. Uma operação definida para números com quatro algarismos, com pelo menos um distinto dos outros, é tal que, quando iterada, converge rapidamente para o número mágico 6174. Apresentamos uma descrição completa do número de iterações necessárias para se chegar ao 6174 e calcula-se o número esperado de iterações quando escolhemos arbitrariamente o núme...
Enurese: Prevalência e Factores Associados em Crianças em Idade Escolar (primei...
Silva, Armandina; Freitas, Alexandre; Oliveira, Paulo; Machado, ElisabeteA enurese nocturna é um problema comum em crianças em idade escolar. Os autores realizaram um estudo com os objectivos de determinar a prevalência da enurese nas crianças do primeiro ciclo no concelho de Vila Nova de Famalicão; identificar factores associados; determinar o impacto da enurese nos pais e nas crianças e identificar os métodos terapêuticos utilizados e a sua eficácia.Efectuou-se um estudo epidemiol...
Sistema de Atravessamento de Passagens Estreitas para um Robot Móvel
Emanuel A. Oliveira; Paulo M. Dias; Vítor M. Santos; Luís AlmeidaIn this article, some solutions that have been developed for the navigation of a mobile robot are presented.These solutions use information perceived by sensors locatedon the robot, only.Using such information, two methods for localisation and navigation were developed. In the first method, called“natural localisation”, the robot uses its sensors to calibrate its position in a previou...
FPGA-based Ethernet Sniffer for Real-Time Networks
João Faria; Arnaldo Oliveira; Paulo Pedreiras; Rui SantosThis paper presents an Ethernet sniffer based on dedicated hardware, able to carry out the timestamping of network events with a level of resolution and precision compatible with the specific needs of real-time protocols. The sniffer is basedin FPGA technology, and autonomously stores in local memory the received messages data and associatedinformation (timestamps and size). This data is then fed to the host co...
SWEET'S SYNDROME - CASE REPORT AND REVIEW OF HOW TO INVESTIGATE AND TREAT
Introduction: Sweet’s syndrome is a neutrophilic dermatosis with acute cutaneous lesions as erythematous edematous plaques and nodules. Other alterations include fever, peripheral leukocytosis, arthralgia, myalgia, cephalea and ophthalmic, oral cavity and internal organs involvement. The purpose of this article is to discuss the clinical condition of the patient, as well as the diagnostic criteria, the approach...
ASHY DERMATOSIS ASSOCIATED WITH ORAL ANTIDEPRESSANTS
Ashy dermatosis or erythema dyschromicum perstans (EDP) is a clinical syndrome with a controversial classification. The condition is rare in Brazil. It was initially reported in El Salvador but has also been found in several South American countries and in other regions of the world. Its etiology is unknown; however, some authors believe that it represents a diffuse presentation of fixed drug eruption, while ot...
Vivências dos doentes e familiares em relação às visitas numa Unidade de Cuidad...
Oliveira, Paulo Alexandre DinisA família é uma unidade básica da organização social e é nela que o indivíduo se forma como ser humano. No caso de ser hospitalizado, toda a família é confrontada com sentimentos de ansiedade, de medo e de stress, os quais os enfermeiros devem estar atentos, durante e após o período de visita. O objectivo deste estudo é compreender as vivências dos doentes e dos familiares no âmbito das visitas numa Unidade de ...
Doxorubicin-Induced Cardiotoxicity: From Bioenergetic Failure and Cell Death to...
Carvalho, Filipa S.; Burgeiro, Ana; Garcia, Rita; Moreno, Antonio J.; Carvalho, Rui A.; Oliveira, Paulo J.Doxorubicin (DOX) is an anticancer anthracycline that presents a dose-dependent and cumulative cardiotoxicity as one of the most serious side effects. Several hypotheses have been advanced to explain DOX cardiac side effects, which culminate in the development of life-threatening cardiomyopathy. One of the most studied mechanisms involves the activation of DOX molecule into a more reactive semiquinone by mitoch...
Inhibition of Mitochondrial Complex III Blocks Neuronal Differentiation and Mai...
Sandro, L. Pereira; Grãos, Mário; Rodrigues, Ana Sofia; Anjo, Sandra I.; Carvalho, Rui A.; Oliveira, Paulo J.; Arenas, Ernest; Ramalho-Santos, JoãoThe mitochondrion is emerging as a key organelle in stem cell biology, acting as a regulator of stem cell pluripotency and differentiation. In this study we sought to understand the effect of mitochondrial complex III inhibition during neuronal differentiation of mouse embryonic stem cells. When exposed to antimycin A, a specific complex III inhibitor, embryonic stem cells failed to differentiate into dopaminer...
Rapeseed oil‑rich diet alters hepatic mitochondrial membrane lipid composition ...
Monteiro, João P.; Pereira, Cláudia V.; Silva, Ana M.; Maciel, Elisabete; Baldeiras, Inês; Peixoto, Francisco; Domingues, Maria R.; Jurado, Amália S.Diet is directly related with physiological alterations occurring at a cell and subcellular level. However, the role of diet manipulation on mitochondrial physiology is still largely unexplored. Aiming at correlating diet with alterations of mitochondrial membrane composition and bioenergetics, Wistar-Han male rats were fed for 11, 22 and 33 days with a rapeseed oil-based diet and mitochondrial bioenergetics, a...
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