l-DOPA alleviates the motor symptoms of Parkinson’s disease, but its long-term use is associated with undesirable dyskinesia. We now tested whether exercise can attenuate this l-DOPA-induced dyskinesia (LID). We tested the effects of exercise on LID in 6-hydroxydopamine hydrochloride-hemiparkinsonian mice. Animals were treated with l-DOPA/benserazide (25/12.5 mg/kg, i.p.) without and with possibility to exercis...
Background: Catenins are adhesion molecules that link cadherin molecules to cytoskeleton. The association of catenins to cadherins is a key step in the function of intact adhesion complexes, and alterations in catenin molecules can lead to the disruption of cell-cell adhesion, resulting in tumour aggressiveness and invasiveness in neoplastic disease. Material and methods: Urothelial lesions were chemically indu...
In this experimental work was studied the effect of Olive leaf addition to diets of New Zealand white X California rabbits (Oryctolagus cuniculus cuniculus) on lipid and liver biochemical parameters.
Chaetomys subspinosus (Olfers, 1818) or bristle-spined porcupine is a species of rodent restricted to the Atlantic Forest of the Eastern Coast of Brazil, vulnerable to extinction. Four specimens captured in the State of Espírito Santo, at the Biological Station of Santa Lúcia (EBSL) and at the State Park Paulo César Vinha (PEPCV), were examined for the presence of ectoparasites. One female and three males of Am...
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