Encontrado 1 documento, a visualizar página 1 de 1

Infection with Mycobacterium ulcerans induces persistent inflammatory responses...

Buruli ulcer (BU) is a devastating, necrotizing, tropical skin disease caused by infections with Mycobacterium ulcerans. In contrast to other mycobacterioses, BU has been associated with minimal or absent inflammation. However, here we show that in the mouse M. ulcerans induces persistent inflammatory responses with viru-lence- dependent patterns. Mycolactone-positive, cytotoxic strains are virulent for mice an...