Encontrados 5 documentos, a visualizar página 1 de 1
Chronic stress disrupts neural coherence between cortico-limbic structures
Oliveira, João F.; Dias, N. S.; Correia, Mariana; Pereira, Filipa Gama; Sardinha, Vanessa Morais; Lima, Ana Raquel; Oliveira, Ana Filipa MartinsThe authors would like to thank Rui Gomes for the help in the application of electrophysio- logical techniques and Luís Martins and Miguel Carneiro for the histological preparations. ; Chronic stress impairs cognitive function, namely on tasks that rely on the integrity of cortico-limbic networks. To unravel the functional impact of progressive stress in cortico-limbic networks we measured neural activity and ...
Neuron-specific proteotoxicity of mutant ataxin-3 in C. elegans: rescue by the ...
Castro, Andreia Cristiana Teixeira de; Ailion, Michael; Jalles, Ana; Brignull, Heather; Vilaça, João L.; Dias, N. S.; Rodrigues, Pedro L.The risk of developing neurodegenerative diseases increases with age. Although many of the molecular pathways regulating proteotoxic stress and longevity are well characterized, their contribution to disease susceptibility remains unclear. In this study, we describe a new Caenorhabditis elegans model of Machado–Joseph disease pathogenesis. Pan-neuronal expression of mutant ATXN3 leads to a polyQ-length dependen...
Effect of medroxy-progesterone acetate on follicular growth and endometrial cyc...
Portela,Valério M.; Farias,Alexandre M.; Moraes,José C. Ferrugem; Gonçalves,Paulo Bayard D.; Veiga,Angela P. Medeiros; Oliveira,João F.The objective of this study was to evaluate the effect of medroxy-progesterone acetate (MAP) with or without estradiol benzoate (EB) on follicular growth during the estrous cycle in cattle. In the first experiment, Hereford cows were synchronized with a synthetic analogue of PGF2 alpha and were treated with two different doses of MAP (250 or 500 mg) with or without EB for 7 days starting on day 8 of the estrous...
Erodibilidade e tensão crítica de cisalhamento em solos de estradas não pavimen...
Oliveira,João F. de; Griebeler,Nori P.; Correchel,Vladia; Silva,Valtercides C. daA falta de um sistema adequado para drenagem de águas pluviais em estradas não pavimentadas é um dos principais fatores que causam a sua degradação e, para que referidos sistemas possam ser adequadamente planejados e dimensionados é necessário o conhecimento de parâmetros de resistência dos solos. Com este trabalho se teve, por objetivo, determinar a erodibilidade e a tensão crítica de cisalhamento para diferen...
Association between reproductive traits and four microsatellites in Brangus-Iba...
Oliveira,João F.C. de; Neves,Jairo P.; Almeida,Eric A.; Steigleder,Clara Sabina; Moraes,José Carlos F.; Gonçalves,Paulo Bayard D.; Weimer,Tania A.The aim of the present study was to verify associations between reproductive efficiency and four microsatellite markers located in synteny with genes involved in the regulation of reproductive mechanisms. A sample of 107 females from a Brangus Ibagé population (5/8 Aberdeen Angus x 3/8 Nelore) was characterized for ETH225 (D9S1) and MM12E6 (D9S20) microsatellites, mapped on chromosome 9, and HEL5 (D21S15) and A...
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