Four-point bending tests are commonly used to assess the fatigue resistance of bi-tuminous bound materials that are used in road pavements. However, it is difficult to establish a reliable relationship between the laboratory test results and the field performance of the mate-rial. In order to predict the real life of the pavement, shift factors are normally used to convert the fatigue results obtained in the la...
Genetic and environmental factors have been implicated in the development of Alzheimer's disease (AD), the most common form of dementia in the elderly. Mutations in 3 genes mapped on chromosomes 21, 14 and 1 are related to the rare early onset forms of AD while the <FONT FACE="Symbol">e</font>4 allele of the apolipoprotein E (APOE) gene (on chromosome 19) is the major susceptibility locus for the most common la...
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