Schistosomiasis is a neglected tropical disease, endemic in 76 countries, that afflicts more than 240 million people. The impact of schistosomiasis on infertility may be underestimated according to recent literature. Extracts of Schistosoma haematobium include estrogen-like metabolites termed catechol-estrogens that down regulate estrogen receptors alpha and beta in estrogen responsive cells. In addition, schis...
OBJECTIVE: To assess the feasibility of a pure endoscopic closure method for vesical perforations using fully absorbable material. MATERIALS AND METHODS: A pilot experimental study was performed in eight anaesthetized female pigs. Four 10-mm and four 20-mm endoscopic full thickness cystotomies were created. An endoscopic suturing machine (RD-180®; LSI Solutions, Victor, NY, USA) was deployed through the workin...
A avaliação do estado redox plasmático, que consiste na determinação simultânea das concentrações plasmáticas de lactato, piruvato, acetoacetato e P-hidroxibutirato, é útil no rastreio das doenças hereditárias do metabolismo por défice energético. O seu doseamento exige rigorosas condições de colheita e processamento das amostras. Fez-se o estudo de 70 crianças sem doença metabólica com idades compreendidas ent...
Odemira é considerado um território de baixa densidade por apresentar uma significativa dispersão territorial (1721Km2, maior concelho português em área geográfica) e uma baixa densidade populacional (15,10hab/km2, num total de 26106 habitantes; INE, 2011). O Município de Odemira entende que o reforço da participação da população nos processos de decisão é um vetor-chave de definição de políticas, de linhas de ...
Nowadays, Aveiro is one of the Portuguese cities where magnificent examples of Art Nouveau movement can be found. Due to construction techniques traditionally used in the area and time period in which the Art Nouveau emerged, most buildings of this style and region were built using adobe blocks, a singularity worldwide. This type of construction has many advantages but also requires particular care to be taken ...
Colorectal carcinoma (CRC) is one of the most common causes of cancer-related mortality. Short-chain fatty acids secreted by dietary propionibacteria from the intestine, such as acetate, induce apoptosis in CRC cells and may therefore be relevant in CRC prevention and therapy. We previously reported that acetic acid-induced apoptosis in Saccharomyces cerevisiae cells involves partial vacuole permeabilization an...
Staphylococcus epidermidis is a commensal bacterium that colonizes the skin and mucous membranes, being the most prevalent staphylococcal species found in humans. However, S. epidermidis has the ability of colonize indwelling medical devices establishing biofilms, which makes this bacteria a common cause of bacteraemia particularly in immunocompromised individuals and neonates [1][2]. The presence of high amoun...
PURPOSE: Precise needle puncture of the renal collecting system is a challenging and essential step for successful percutaneous nephrolithotomy (PCNL). This works aims to evaluate the efficiency of a new real-time electromagnetic tracking (EMT) system for in vivo kidney puncture. MATERIALS AND METHODS: Six anesthetized female pigs underwent ureterorenoscopies in order to place a catheter with an EMT sensor into...
PURPOSE: Precise needle puncture of the renal collecting system is a challenging and essential step for successful percutaneous nephrolithotomy (PCNL). This works aims to evaluate the efficiency of a new real-time electromagnetic tracking (EMT) system for in vivo kidney puncture. MATERIALS AND METHODS: Six anesthetized female pigs underwent ureterorenoscopies in order to place a catheter with an EMT sensor into...
The evaluation of site effects on a broad scale is a critical issue for seismic hazard and risk assessment, land use planning and emergency planning. As characterization of site conditions based on the shear-wave velocity has become increasingly important, several methods have been proposed in the literature to estimate its average over the first thirty meters (Vs30) from more extensively available data. These ...
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