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In vivo efficiency evaluation of a phage cocktail in controlling severe colibac...
Oliveira, Ana Cristina Afonso; Sereno, R.; Azeredo, JoanaInfections caused by avian pathogenic Escherichia coli (APEC) cause important economic losses to poultry industry. The studies presented herein, aimed at investigating the in vivo performance of a cocktail of three phages in treating severe respiratory E. coli infections in experimentally contaminated birds and naturally infected flocks. Three lytic coliphages, phi F78E (Myoviridae), phi F258E (Siphoviridae) an...
Development of a bacteriophage based product to control colibacillosis in poultry
Oliveira, Ana Cristina AfonsoTese de doutoramento em Engenharia Química e Biológica ; Escherichia coli (E. coli) is part of the commensal microflora of the chicken intestinal tract, being commonly an opportunistic bacteria that causes disease in immunologic deprived chickens. However, there are extra-intestinal E. coli strains, the avian pathogenic Escherichia coli (APEC) that are able to cause colibacillosis by itself, due to its invasiv...
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