Encontrados 2 documentos, a visualizar página 1 de 1
Immunocytochemical expression of p16 INK4A and Ki-67 in cytologically negative ...
Longatto Filho, Adhemar; Utagawa, Maria Lúcia; Shirata, Neuza Kasumi; Pereira, Sónia Maria Miranda; Namiyama, Gislene; Kanamura, Cristina TakamiThis study was designed to analyze the cross-sectional comparison of the p16 INK4A and Ki-67 immunocytochemical expression in negative and equivocal (atyp-ical squamous cells of undetermined significance (ASC-US)) liquid-based cytology (LBC) samples testing positive for high-risk human papillomavirus (HPV) types with HC2 assay or polymerase-chain reaction (PCR). A series of 199 consecutive LBC speci-mens derive...
P53 and Rb tumor suppressor gene alterations in gastric cancer
Mattar,Rejane; Nonogaki,Suely; Silva,Cleonice; Alves,Venancio; Gama-Rodrigues,Joaquim J.Inactivation of tumor suppressor genes has been frequently observed in gastric carcinogenesis. Our purpose was to study the involvement of p53, APC, DCC, and Rb genes in gastric carcinoma. METHOD: Loss of heterozygosity of the p53, APC, DCC and Rb genes was studied in 22 gastric cancer tissues using polymerase chain reaction; single-strand conformation polymorphism of the p53 gene exons 5-6 and exons 7-8 was st...
| Financiadores do RCAAP | |||||||
|
|
|
|
|
|
||