Encontrados 26 documentos, a visualizar página 1 de 3
Total laparoscopic hysterectomy: retrospective analysis of 262 cases
Nogueira-Silva, C; Santos-Ribeiro, S; Barata, S; Alho, C; Osório, F; Calhaz-Jorge, JINTRODUCTION: Hysterectomy is one of the most common gynecological procedures and may be performed either by vaginal approach, laparotomy or laparoscopy. Although total laparoscopic hysterectomy has multiple advantages, conflicting major complication rates have been previously reported. OBJECTIVES: To describe our experience performing TLH and to evaluate complication rates. MATERIAL AND METHODS: A retrospectiv...
Improving fECG signal acquisition in the evaluation of fetal well-being
Gonçalves, C.; Sousa, J.; Nogueira-Silva, C.; Simões, RicardoThe ability to monitor fetal heart rate is vital during late pregnancy and labor in order to evaluate fetal well-being. Current monitoring practice is essentially based on external cardiotocography and, less frequently, during labor, invasive fetal scalp electrocardiography. Many current and envisaged applications could benefi t from simpler devices using a 3-lead ECG confi guration. We are designing a maternit...
The impact of GGH -401C>T polymorphism on cisplatin-based chemoradiotherapy res...
Silva, IH; Nogueira-Silva, C; Figueiredo, T; Lombo, L; Faustino, I; Catarino, R; Nogueira, A; Nogueira, D; Medeiros, RAIMS: Cervical cancer is the third most frequent cancer in women worldwide, mostly treated with cisplatin-based chemoradiotherapy. Since it is known that folate metabolism might interfere with cisplatin effectiveness, we intended to study the influence of the Gamma Glutamyl Hydrolase -401C>T polymorphism in treatment response in cervical cancer. METHODS: We retrospectively reviewed the clinical data of 167 pat...
The role of glycoprotein 130 family of cytokines in fetal rat lung development
Nogueira-Silva, C; Piairo, P; Carvalho-Dias, E; Veiga, C; Moura, RS; Correia-Pinto, JThe glycoprotein 130 (gp130) dependent family of cytokines comprises interleukin-6 (IL-6), IL-11, leukemia inhibitory factor (LIF), cardiotrophin-like cytokine (CLC), ciliary neurotrophic factor (CNTF), cardiotrophin-1 (CT-1) and oncostatin M (OSM). These cytokines share the membrane gp130 as a common signal transducer. Recently, it was demonstrated that IL-6 promotes, whereas LIF inhibits fetal lung branching....
The impact of GGH -401C>T polymorphism on cisplatin-based chemoradiotherapy res...
Silva, IH; Nogueira-Silva, C; Figueiredo, T; Lombo, L; Faustino, I; Catarino, R; Nogueira, A; Pereira, D; Medeiros, RAIMS: Cervical cancer is the third most frequent cancer in women worldwide, mostly treated with cisplatin-based chemoradiotherapy. Since it is known that folate metabolism might interfere with cisplatin effectiveness, we intended to study the influence of the Gamma Glutamyl Hydrolase -401C>T polymorphism in treatment response in cervical cancer. METHODS: We retrospectively reviewed the clinical data of 167 pati...
The impact of GGH -401C>T polymorphism on cisplatin-based chemoradiotherapy res...
Silva, IH; Nogueira-Silva, C; Figueiredo, T; Lombo, L; Faustino, I; Catarino, R; Nogueira, A; Nogueira, D; Medeiros, RAIMS: Cervical cancer is the third most frequent cancer in women worldwide, mostly treated with cisplatin-based chemoradiotherapy. Since it is known that folate metabolism might interfere with cisplatin effectiveness, we intended to study the influence of the Gamma Glutamyl Hydrolase -401C>T polymorphism in treatment response in cervical cancer. METHODS: We retrospectively reviewed the clinical data of 167 pat...
The role of glycoprotein 130 family of cytokines in fetal rat lung development
Nogueira-Silva, C; Piairo, P; Carvalho-Dias, E; Veiga, C; Moura, RS; Correia-Pinto, JThe glycoprotein 130 (gp130) dependent family of cytokines comprises interleukin-6 (IL-6), IL-11, leukemia inhibitory factor (LIF), cardiotrophin-like cytokine (CLC), ciliary neurotrophic factor (CNTF), cardiotrophin-1 (CT-1) and oncostatin M (OSM). These cytokines share the membrane gp130 as a common signal transducer. Recently, it was demonstrated that IL-6 promotes, whereas LIF inhibits fetal lung branching....
The impact of GGH -401C>T polymorphism on cisplatin-based chemoradiotherapy res...
Silva, IH; Nogueira-Silva, C; Figueiredo, T; Lombo, L; Faustino, I; Catarino, R; Nogueira, A; Pereira, D; Medeiros, RAIMS: Cervical cancer is the third most frequent cancer in women worldwide, mostly treated with cisplatin-based chemoradiotherapy. Since it is known that folate metabolism might interfere with cisplatin effectiveness, we intended to study the influence of the Gamma Glutamyl Hydrolase -401C>T polymorphism in treatment response in cervical cancer. METHODS: We retrospectively reviewed the clinical data of 167 pati...
Optimizing electrode positioning in 3-lead ECG chest devices
Simões, Ricardo; Sousa, Joana; Nogueira-Silva, C.; Gamboa, HugoAlthough the 12-lead electrocardiogram has become an essential medical and research tool, many current and envisaged applications would benefit from simpler devices, using 3-lead ECG configuration. This is particularly true for Ambient Assisted Living (in a broad perspective). However, the chest anatomy of female patients, namely during pregnancy, can hamper the adequate placement of a 3-lead ECG device and, ve...
Local fetal lung renin-angiotensin system as a target to treat congenital diaph...
Nogueira-Silva, C; Carvalho-Dias, C; Piairo, P; Nunes, S; Baptista, MJ; Moura, RS; Correia-Pinto, JAntenatal stimulation of lung growth is a reasonable approach to treat congenital diaphragmatic hernia (CDH), a disease characterized by pulmonary hypoplasia and hypertension. Several evidences from the literature demonstrated a possible involvement of renin-angiotensin system (RAS) during fetal lung development. Thus, the expression pattern of renin, angiotensin-converting enzyme, angiotensinogen, type 1 (AT₁)...
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