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PHEOCHROMOCYTOMA AND NEUROFIBROMATOSIS 1
Introduction: Pheochromocytomas are tumours arising from chromaffin cells in the sympathetic nervous system. Clinical manifestations are protean, function of the variable secretory profile of several compounds including catecolamines, neuropeptides and other vasoactive molecules. Neurofibromatosis I (von Recklinghausen`s disease), a prevalent autosomal dominant disorder, is the most prevalent type among the neu...
Intra-gastric ballon in the treatment of morbid obesity.
Carvalho, Ma Raquel; Jorge, Zulmira; Nobre, Ema; Dias, Teresa; Cortez-Pinto, Helena; Machado, Mariana V; Camolas, José; Neves, Sílvia; Guerra, AnabelaIntragastric balloon is a temporary treatment for weight loss with proven safety and efficacy when associated with lifestyle intervention. It is indicated in the super--obese who are candidates for bariatric surgery to lose weight and to reduce their high surgical risk. Our aim was to retrospectively evaluate the results of the patients in whom this device was inserted during a three-year period from the beginn...
A rare case of hyperandrogenism: bilateral Leydig cell tumor of the ovary.
Marcelino, M; Nobre, Ema; Conceição, J; Lopes, L; Vilar, H; França Martins, M; Carvalho, A; André, S; Horta, A; De Castro, J JácomeThe androgen-secreting tumors constitute fewer than 1% of ovarian tumors. Leydig cell tumor is one of the most common of this type of lesion and it is usually benign, small and unilateral.A 67 year old woman was referred to the Endocrine clinic due to hirsutism (score 22 Ferriman-Gallwey) and male type alopecia with 3 years of evolution and progressive worsening. Biochemically she had high levels of serum testo...
Autoimmune thyroid disease: a case report.
Jorge, Zulmira; Serviço de Endocrinologia, Diabetes e Metabolismo, Hospital Militar Principal, Lisboa.; Nobre, Ema Lacerda; Santana, AAutoimmune thyroid disease is the most common cause of subclinical thyroid dysfunction (hypo and hyperthyroidism) in the western countries. Autoimmune thyroid diseases with clinical relevance (Graves' disease and autoimmune hypothyroidism) are common and can present with a large clinical and laboratorial spectrum. Hypo and hyperthyroidism can exist in the same patient, on different times. Progression from Grave...
Assessment of an obesity clinic in a center hospital.
Vasconcelos, Maria P; Jorge, Zulmira; Nobre, Ema L; Domingues, Andreia; Macedo, Ana; Castro, J Jácome deSlight weight losses (5%) are consensually accepted as important in the treatment of obesity today. Some authors also consider that maintaining weight is an indicator of success in the treatment of this condition.Characterisation and assessment of changes in weight in obese patients monitored at an obesity clinic in a hospital endocrinology department.Retrospective analysis of the clinical files of the Endocrin...
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