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Modulation of MicroRNA-194 and cell migration by HER2-targeting trastuzumab in ...

Le, Xiao-Fen; Almeida, Maria Inês; Mao, Weiqu; Spizzo, Riccardo; Rossi, Simona; Nicoloso, Milena S.; Zhang, Shu; Wu, Yun; Calin, George A.

Conceived and designed the experiments: XFL GAC RCB. Performed the experiments: XFL MIA WM RS MSN SZ. Analyzed the data: XFL SR. Contributed reagents/materials/analysis tools: YW GAC. Wrote the paper: XFL RCB. ; Trastuzumab, a humanized monoclonal antibody directed against the extracellular domain of the HER2 oncoprotein, can effectively target HER2-positive breast cancer through several mechanisms. Although t...


Strand-specific miR-28-5p and miR-28-3p have distinct effects in colorectal can...

Almeida, Maria L.; Nicoloso, Milena S.; Zeng, Lizhi; Ivan, Cristina; Spizzo, Riccardo; Gafà, Roberta; XIiao, LIianchun; Zhang, Xinna; Vanninii, Ivan

The authors thank Sue Moreau from the Department of Scientific Publications at The University of Texas MD Anderson Cancer Center for English language editing of the manuscript. Author contributions: Study concept and design: M.I.A., P.A.Z, G.A.C. Acquisition of data: M.I.A., L.Z., X.Z. Drafting of the manuscript: M.I.A., M.N., R.S., M.F., R.M.R., P.A.Z, G.A.C. Analysis and interpretation of data: M.I.A., M.N., ...


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia