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Effect of Skin Sensitizers on Inducible Nitric Oxide Synthase Expression and Ni...
Cruz, M. T.; Neves, B. M.; Gonçalo, M.; Figueiredo, A.; Duarte, C. B.; Lopes, M. C.Nitric oxide (NO) is involved in the pathogenesis of acute and chronic inflammatory conditions, namely in allergic contact dermatitis (ACD). However, the mechanism by which NO acts in ACD remains elusive. The present study focuses on the effects of different contact sensitizers (2,4-dinitrofluorbenzene, 1,4-phenylenediamine, nickel sulfate), the inactive analogue of DNFB, 2,4-dichloronitrobenzene, and two irrit...
Data: 2007
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Origem: Estudo Geral - Universidade de Coimbra
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