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Characterization of rat heart alkaline phosphatase isoenzymes and modulation of...
Mota,A.; Silva,P.; Neves,D.; Lemos,C.; Calhau,C.; Torres,D.; Martel,F.; Fraga,H.; Ribeiro,L.; Alçada,M.N.M.P.; Pinho,M.J.; Negrão,M.R.; Pedrosa,R.Alkaline phosphatase (ALP) is important in calcification and its expression seems to be associated with the inflammatory process. We investigated the in vitro acute effects of compounds used for the prevention or treatment of cardiovascular diseases on total ALP activity from male Wistar rat heart homogenate. ALP activity was determined by quantifying, at 410 nm, the p-nitrophenol released from p-nitrophenylpho...
Human serum alcaline phosphatase and ageing.
Negrão, M R; Martins, M J; Ramos, E; Barros, H; Hipólito-Reis, C; Azevedo, IIn experimental ageing models an inverse relationship between age and alkaline phosphatase activity has been observed.To characterize serum levels of alkaline phosphatase activity in humans according to age and gender.Serum alkaline phosphatase was determined in a random sample of 203 community dwellers aged 40 or more years.In men (n=87) total serum alkaline phosphatase markedly increased from the 5th to the 6...
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