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Hypovitaminosis D in Patients Admitted to an Internal Medicine Ward
Santiago, Tânia; Rebelo, Marta; Porto, João; Silva, Nuno; Vieira, José; Nascimento Costa, J MIntroduction: Hypovitaminosis D (hypoD) is a vitamin deficiency that has been rising in the developed countries, due not only to inappropriate eating habits, but also because of lower sun exposure and lack of exercise. Objective: To determine the prevalence of vitamin D deficiency and to analyze associated factors, in patients admitted to an Internal medicine Ward. Methods: Cross-sectional study which included ...
Digital ulcers in systemic sclerosis: use of endotheline antagonists.
Mota, Joana; Castellano, Amparo; Santiago, Felicidade; Carvalho, Patrícia; Madeira, A Sofia; Pereira De Moura, J M; Nascimento Costa, J MSystemic sclerosis (SSc) is a systemic disease, characterized by fibrosis and vasculopathy, with variable internal organ involvement. Skin is very often involved, namely digital ulcers (DU), seldom treatment resistant, responsible for important functional limitation. The DU can evolve from sclerodactily with superficial ulcers, isquemic lesions, deep necrosis, gangrene, loss of tissue, and consequently, to fing...
Undifferentiated osteoclastic-type giant cell carcinoma.
Pimentel, Ana; Leitão, Sara; Dias, Nuno; Cipriano, Maria Augusta; Leite, Júlio; Santos, Rui Marques; Nascimento Costa, J MInitially described 40 years ago (Rosai), the undifferentiated osteoclastic-type giant cell carcinoma (IOGCC) is a variant of ductal adenocarcinoma and accounts for less than 1% of exocrine pancreatic tumors. Its extreme rarity, with consequent existence of few reports and clinical experience, leads to the arousal of doubts with regard to its histogenesis, types of approach and therapeutical attitudes. It is im...
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