Encontrados 55 documentos, a visualizar página 1 de 6
Efectividade da Rede de Referenciação Perinatal da Região Centro
Costa, E.; Moleiro, P.; Carvalho, L.; Neves, F.; Oliveira, J.; Ventura, A.; Teixeira, A. L.; Martins, J.; Figueiredo, N.; Costa, R.; Peixoto, J.Resumo Em 1990 foi desenvolvida em Portugal uma Rede de Referenciação Perinalal, com definição dos limites e as responsabilidades assistenciais dos Hospitais de Apoio Perinatal Diferenciado (HAPD) e dos Hospitais de Apoio Perinatal (HAP). Graças ao espírito de cooperação c complementaridade desenvolvidos, os critérios de transferência iu útero e pós natal estão bem estabelecidos* Com os resultados do Registo Na...
Immunoglobulin genes implicated in glioma risk
Pandey, JP; Kaur, N; Costa, N; Amorim, J; Nabico, R; Linhares, P; Vaz, R; Viana-Pereira, M; Reis, RMBoth genetic and environmental factors are thought to be causal in gliomagenesis. Several genes have been implicated in glioma development, but the putative role of a major immunity-related gene complex member, immunoglobulin heavy chain γ (IGHG) has not been evaluated. Prior observations that IGHG-encoded γ marker (GM) allotypes exhibit differential sensitivity to an immunoevasion strategy of cytomegalovirus...
Gitelman syndrome
Cotovio, P; Silva, C; Oliveira, N; Costa, FHypokalaemia is a common clinical disorder, the cause of which can usually be determined by the patient's clinical history. Gitelman syndrome is an inherited tubulopathy that must be considered in some settings of hypokalaemia. We present the case of a 60-year-old male patient referred to our nephrology department for persistent hypokalaemia. Clinical history was positive for symptoms of orthostatic hypotension...
Antitumor activity of hierridin B, a cyanobacterial secondary metabolite found ...
Leão, Pedro N.; Costa, Margarida; Ramos, Vitor; Pereira, Alban R.; Fernandes, Virginia C.; Domingues, Valentina F.; Gerwick, William H.Cyanobacteria are widely recognized as a valuable source of bioactive metabolites. The majority of such compounds have been isolated from so-called complex cyanobacteria, such as filamentous or colonial forms, which usually display a larger number of biosynthetic gene clusters in their genomes, when compared to free-living unicellular forms. Nevertheless, picocyanobacteria are also known to have potential to pr...
Antitumor activity of hierridin B, a cyanobacterial secondary metabolite found ...
Leão, Pedro N.; Costa, Margarida; Ramos, Vitor; Pereira, Alban R.; Fernandes, Virgínia C.; Domingues, Valentina F.; Gerwick, William H.Cyanobacteria are widely recognized as a valuable source of bioactive metabolites. The majority of such compounds have been isolated from so-called complex cyanobacteria, such as filamentous or colonial forms, which usually display a larger number of biosynthetic gene clusters in their genomes, when compared to free-living unicellular forms. Nevertheless, picocyanobacteria are also known to have potential to pr...
Nanostructured 3D constructs based on chitosan and chondroitin sulphate multila...
Silva, Joana M.; Georgi, N.; Costa, Rui; Praveen, S.; Reis, R. L.; Blitterswijk, C. A. van; Karperien, M.; Mano, J. F.Nanostructured three-dimensional constructs combining layer-by-layer technology (LbL) and template leaching were processed and evaluated as possible support structures for cartilage tissue engineering. Multilayered constructs were formed by depositing the polyelectrolytes chitosan (CHT) and chondroitin sulphate (CS) on either bidimensional glass surfaces or 3D packet of paraffin spheres. 2D CHT/CS multi-layered...
Avaliação experimental do comportamento sísmico de casas de madeira
Lourenço, Paulo B.; Branco, Jorge M.; Mendes, N.; Costa, A. C.; Candeias, PauloAs casas de madeira estão a ter um desenvolvimento rápido na Europa devido a aspetos tais como a sustentabilidade e o elevado grau de industrialização e prefabricação, que se traduzem em facilidade e rapidez de montagem. Os sistemas mais tradicionais de estruturas de madeira e os sistemas inovadores recentes são agora aplicados não apenas no norte da Europa mas, crescentemente, no sul da Europa, onde a perigosi...
A case of systemic pseudohypoaldosteronism with a novel mutation in the SCNN1A ...
Silva, N; Costa, M; Silva, A; Sá, C; Martins, S; Antunes, A; Marques, O; Castedo, S; Pereira, AWe report a neonatal case of systemic pseudohypoaldosteronism type 1 caused by a novel mutation in the SCNN1A gene (homozygous c.1052+2dupT in intron 3) in which the patient presented with life-threatening hyperkalemia, hyponatremia and metabolic acidosis. It remains uncertain if there is genotype-phenotype correlation, due to the rarity of the disease. This mutation, which to our best knowledge has not been de...
Leaf temperature and photosynthetic performance in chickpea
Pinheiro, C; Simões, N; Costa, M; Toureiro, A; Ribeiro, IC; Lourenço, ME; Silva, LL; Duarte, I; Chaves, MMThe responses of photosynthetic rate and leaf conductance to leaf temperature were evaluated in two contrasting chickpea genotypes (Elixir and FLIP03-46C) grown under field conditions (Elvas, Portugal). Photosynthetic performance was assayed with leaf temperatures ranging from 24ºC to 40º C under controlled VPD. Technical constraints and physiological implications are discussed.
Inter-annual variations of macrobenthic communities over three decades in a lan...
Correia, M.J.; Costa, J.L.; Chainho, P.; Félix, P.M.; Chaves, M.L.; Medeiros, J.P.; Silva, G.; Azeda, C.; P. Tavares, P.; Costa, A.; Costa, A.M.Santo André is an enclosed brackish water coastal lagoon with temporary connections to the sea by a man-made channel. The exchange and mixture of saltwater and freshwater is irregular and the lagoon may show daily and seasonal fluctuations, but also long-term variation. Different benthic communities may be present along the annual cycle according to the magnitude of episodic freshwater and sea water inputs. In ...
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