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Gold nanoparticles functionalised with stable, fast water exchanging Gd3+ chela...
Ferreira, Miguel Filipe Moreira Marques; Mousavi, Bibimaryam; Ferreira, Paula M. T.; Martins, Catarina; Helm, Lothar; Martins, José A.Gold nanoparticles functionalized with Gd3+ chelates displaying fast water exchange, superb pH stability and inertness towards transmetalation with Zn2+ have been prepared and characterized as a new high relaxivity (29 mM-1s-1, 30 MHz, 25 ºC) Contrast Agent potentially safe for in vivo MRI applications. The Lipari-Szabo treatment for internal rotation was used to evaluate the effect of linker flexibility on the...
Data: 2012
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Origem: RepositóriUM - Universidade do Minho
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