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Chitosan-based dressings loaded with neurotensin—an efficient strategy to impro...
Moura, Liane I. F.; Dias, Ana M. A.; Leal, Ermelindo C.; Carvalho, Lina; Sousa, Hermínio C. de; Carvalho, EugéniaOne important complication of diabetes mellitus is chronic, non-healing diabetic foot ulcers (DFUs). This study aims to develop and use dressings based on chitosan derivatives for the sustained delivery of neurotensin (NT), a neuropeptide that acts as an inflammatory modulator in wound healing. Three different derivatives, namely N-carboxymethyl chitosan, 5-methyl pyrrolidinone chitosan (MPC) and N-succinyl chi...
Data: 2014
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Origem: Estudo Geral - Universidade de Coimbra
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