Encontrados 2 documentos, a visualizar página 1 de 1
Chitosan-based dressings loaded with neurotensin—an efficient strategy to impro...
Moura, Liane I. F.; Dias, Ana M. A.; Leal, Ermelindo C.; Carvalho, Lina; Sousa, Hermínio C. de; Carvalho, EugéniaOne important complication of diabetes mellitus is chronic, non-healing diabetic foot ulcers (DFUs). This study aims to develop and use dressings based on chitosan derivatives for the sustained delivery of neurotensin (NT), a neuropeptide that acts as an inflammatory modulator in wound healing. Three different derivatives, namely N-carboxymethyl chitosan, 5-methyl pyrrolidinone chitosan (MPC) and N-succinyl chi...
Improved Survival, Vascular Differentiation and Wound Healing Potential of Stem...
Pedroso, Dora C. S.; Tellechea, Ana; Moura, Liane; Fidalgo-Carvalho, Isabel; Duarte, João; Carvalho, Eugénia; Ferreira, LinoIn this study, we developed a methodology to improve the survival, vascular differentiation and regenerative potential of umbilical cord blood (UCB)-derived hematopoietic stem cells (CD34+ cells), by co-culturing the stem cells in a 3D fibrin gel with CD34+-derived endothelial cells (ECs). ECs differentiated from CD34+ cells appear to have superior angiogenic properties to fully differentiated ECs, such as huma...
| Financiadores do RCAAP | |||||||
|
|
|
|
|
|
||