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Exploratory assessment of groundwater vulnerability to pollution in the Sordo R...

CD4+, CD8+ AND CD19+ Cells at Individuals with Dyslipidemia

Introduction: The past decade has witnessed an increasing recognition that inflammatory mechanisms play a central role in the pathogenesis of atherosclerosis and its complications. Recently, attention was focused on the potential role of plasma markers of inflammation as risk predictors among those at risk for cardiovascular events. Of these potential markers, C-reactive protein (CRP), IL6, metalloproteinases, ...

Digital ulcers in systemic sclerosis: use of endotheline antagonists.

Systemic sclerosis (SSc) is a systemic disease, characterized by fibrosis and vasculopathy, with variable internal organ involvement. Skin is very often involved, namely digital ulcers (DU), seldom treatment resistant, responsible for important functional limitation. The DU can evolve from sclerodactily with superficial ulcers, isquemic lesions, deep necrosis, gangrene, loss of tissue, and consequently, to fing...

Energy in an expanding universe in the teleparallel geometry

The main purpose of this paper is to explicitly verify the consistency of the energy-momentum and angular momentum tensor of the gravitational field established in the Hamiltonian structure of the Teleparallel Equivalent of General Relativity (TEGR). In order to reach these objectives, we obtained the total energy and angular momentum (matter plus gravitational field) of the closed universe of the Friedmann-Lem...

Rochas xistentas de Trás-os-Montes como recurso

The abundance of schist outcrops in the Northeast and Centre regions of Portugal made schist, in the past, a common building material. A FCT R&D project is in course aiming the structural, mineralogical, petrographycal and technological characterization of the schist occurrences in NE Portugal and the promotion of those schistose rocks as a geological resource. In this contribution, we present three cases corre...

CHEMOKINE RECEPTOR REPERTOIRE REFLECTS MATURE T-CELL LYMPHOPROLIFERATIVE DISORD...

The World Health Organisation classification of mature T-cell lymphoproliferative disorders, combines clinical, morphological and immunophenotypic data. The later majorly contributes for the classification, as well as to the understanding of the malignant T-cell behaviour. The fact that T-cell migration is regulated by chemokines should, in theory, enable us to identify tissue tropism and organ involvement by n...

HUMAN BLOOD T AND NK CELL IN VITRO STIMULATION REVEALS A SIMILAR ACTIVATION PHE...

The complexity of T and NK-cell responses needs a great deal of control in the way these cells respond to stimulation. This is made by a precise regulation of gene expression leading to specific changes of membrane proteins, in order to acquire their full cytotoxic or immunological mediators secreting potential. The immunophenotypic changes occurring in-vivo on blood T and NK-cells in patients with acute and ch...

Application of the End Loaded Split and Single-Leg Bending Tests to the Mixed-M...

Produção de gergelim orgânico nas comunidades de produtores familiares de São F...

A cultura do gergelim (Sesamum indicum L.) constitui-se em alternativa de grande importância econômica e social para as condições semi-áridas do Nordeste brasileiro, por ser de fácil cultivo, apresentar tolerância a estiagem e, principalmente, por gerar renda e trabalho e por ser fonte de alimento para pequenos e médios produtores. As áreas do Semi-Árido do Nordeste brasileiro destacam-se como possuidoras de co...

Abordagem perioperatória do doente diabético

A hiperglicemia é um achado comum em doentes hospitalizados, com ou sem diagnóstico prévio de diabetes, sendo recentemente considerada um marcador independente de mau prognóstico e de elevada mortalidade. O controlo agressivo dos níveis de glicemia tem sido reconhecido em múltiplos trabalhos de referência como um importante alvo terapêutico na doença aguda grave, associado a melhoria dos resultados clínicos e a...