Marine organisms and materials exhibit interesting properties for their use in biomedical applications, following biomimetic approaches [1,2]. For instance, the white seabass (Lates Calcarifer) scales exhibit a very interesting pattern, which inspire their use as a guiding platform for cellular growth, in a tissue regeneration approach. Moreover, fish scales are composed of hydroxyapatite and type I collagen fi...
Avaliaram-se a composição química e a cinética da digestibilidade ruminal in situ da matéria seca (MS), proteína bruta (PB) e fibra em detergente neutro (FDN) da forragem de quatro espécies de Brachiaria, com 56 dias de crescimento, coletadas por corte manual. Foram utilizadas três vacas mestiças Holandês x Zebu, fistuladas no rúmen. Foram observados teores de 21,0; 21,1; 20,5 e 19,6% de MS; 7,5; 6,4; 6,8 e 7,0...
The positive interaction of materials with tissues is an important step in regenerative medicine strategies. Hydrogels that are obtained from polysaccharides and proteins are expected to mimic the natural cartilage environment and thus provide an optimum milleu for tissue growth and regeneration. In this work, novel hydrogels composed of blends of chitosan and Bombyx mori silk fibroin were cross-linked with gen...
Nanometric silk-fibroin nets were fabricated by electrospinning from regenerated Bombyx mori silk-fibroin (SF)/formic acid solutions with the addition of genipin (GE), 2, 15 and 24 h after the solution preparation. After spinning, the pure fibroin nanofibers were water soluble and needed a further stabilization process, whereas the reaction of fibroin with genipin resulted in water-insoluble fibroin nets due to...
Uma cadela da raça Pinscher Miniatura foi medicada pelo proprietário com enrofloxacina, na dose de 50mg/kg, uma vez ao dia, por dois dias (dose diária 10 vezes maior que a prescrita). Ao exame clínico o animal apresentou-se deprimido, em cifose lombar, hipotérmico, com mucosas pálidas, dispnéia, sialorréia, vômitos e anúria, evoluindo para parada respiratória, convulsões e coma. Foi realizado tratamento sintomá...
Few data are available in the literature regarding the effect of pentosan polysulfate (PPS) on normal and fibrotic rat livers. In addition, the combination of PPS and carbon tetrachloride (CCl4) has not been studied so far. The objective of this study was to assess the effect of PPS on rat livers treated or not with CCl4 for the induction of liver fibrosis. The study consisted of four stages: 1) hepatic fibrosi...
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