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Prognostic Value of VEGF in Patients Submitted to Percutaneous Coronary Interve...

Ramos, C; Napoleão, P; Selas, M; Freixo, C; Viegas Crespo, AM; Mota Carmo, M; Cruz Ferreira, R; Pinheiro, T

We examined the longitudinal changes of VEGF levels after percutaneous coronary intervention for predicting major adverse cardiac events (MACE) in coronary artery disease (CAD) patients. VEGF was measured in 94 CAD patients' serum before revascularization, 1-month and 1-year after. Independently of clinical presentation, patients had lower VEGF concentration than a cohort of healthy subjects (median, IQ: 15.9, ...


Optimal Cut-Off Value for Homeostasis Model Assessment (HOMA) Index of Insulin-...

Timóteo, AT; Miranda, F; Mota Carmo, M; Cruz Ferreira, R

INTRODUCTION: Insulin resistance is the pathophysiological key to explain metabolic syndrome. Although clearly useful, the Homeostasis Model Assessment index (an insulin resistance measurement) hasn't been systematically applied in clinical practice. One of the main reasons is the discrepancy in cut-off values reported in different populations. We sought to evaluate in a Portuguese population the ideal cut-off ...


Carotid Intima-Media Thickness and Carotid Plaques Improves Prediction of Obstr...

Timóteo, AT; Mota Carmo, M; Cruz Ferreira, R

Does carotid intima-media thickness (cIMT), a surrogate marker of cardiovascular events, have predictive incremental value over established risk factors for stable coronary artery disease (CAD)? Prospective study of 300 patients, with suspected stable CAD, admitted for an elective coronary angiography and carotid ultrasound. The CAD patients had a higher cIMT, which showed a modest predictive accuracy for CAD (...


Does Metabolic Syndrome Predict Significant Angiographic Coronary Artery Disease?

Timóteo, AT; Mota Carmo, M; Cruz Ferreira, R

INTRODUCTION: Metabolic syndrome (MS) is an independent predictor of acute cardiovascular events. However, few studies have addressed the relationship between MS and stable angiographic coronary artery disease (CAD), which has a different pathophysiological mechanism. We aimed to study the independent predictors for significant CAD, and to analyze the impact of MS (by the AHA/NHLBI definition) on CAD. METHODS:...


Prevalence of Metabolic Syndrome and Diabetes on a High-Risk Population with Su...

Timóteo, AT; Mota Carmo, M; Cruz Ferreira, R

Objectivos: A prevalência de Sindroma Metabólica (SM) e diabetes é variável consoante a definição utilizada, assim como com a região geográfica e o grupo étnico estudado. Não existem estudos em indivíduos portugueses com suspeita de doença arterial coronária. Analisámos a prevalência de SM e diabetes nesta população específica de doentes, comparando também definições. Métodos: Incluíram-se no estudo 300 indivíd...


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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia