Encontrados 3 documentos, a visualizar página 1 de 1
Dioxin-induced acute cardiac mitochondrial oxidative damage and increased activ...
Pereira, Susana P.; Pereira, Gonçalo C.; Pereira, Cláudia V.; Carvalho, Filipa S.; Cordeiro, Marília H.; Mota, Paula C.; Ramalho-Santos, J.The environmental dioxin 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is classified as a Group 1 human carcinogen and teratogenic agent.We hypothesize that TCDD-induced oxidative stress may also interfere with mitochondrial ATP-sensitive potassium channels (mitoKATP), which are known to regulate and to be regulated by mitochondrial redox state. We investigated the effects of an acute treatment of male Wistar rats...
Testicular mitochondrial alterations in untreated streptozotocin-induced diabet...
Amaral, Sandra; Mota, Paula C.; Lacerda, Beatriz; Alves, Marco; Pereira, Maria de Lourdes; Oliveira, Paulo J.; Ramalho-Santos, Joãohttp://www.sciencedirect.com/science/article/B6W8G-4V3HFCC-2/2/73c61572e33e945983a6914b2dfbeb63
Comparison between different markers for sperm quality in the cat: Diff-Quik as...
Mota, Paula C.; Ramalho-Santos, JoãoThe majority of wild felids, as well as some domestic cats, have low sperm concentration in their ejaculates, and a high proportion of abnormal spermatozoa. We have employed several possible semen quality markers to further characterize cat epididymal sperm. Methods included possible apoptotic reporters, such as the annexin V assay to monitor exposure of phosphatidylserine (PS) on the outer leaflet of the plasm...
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