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Contact sensitizers downregulate the expression of the chemokine receptors CCR6...
Cruz, M. T.; Gonçalo, M.; Paiva, A.; Morgado, J. M.; Figueiredo, A.; Duarte, C. B.; Lopes, M. C.Chemokines are involved in the control of dendritic cell (DC) trafficking, which is critical for the immune response, namely in allergic contact dermatitis (ACD). In this work, we investigated by flow cytometry the effect of the contact sensitizers 2,4-dinitrofluorobenzene (DNFB), 1,4-phenylenediamine (PPD) and nickel sulfate (NiSO4), on the surface expression of the chemokine receptors CCR6 and CXCR4 in DC. As...
Data: 2005
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Origem: Estudo Geral - Universidade de Coimbra
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