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Breast Cancer Presents With a Paraneoplastic Neurologic Syndrome

Coelho Barata, P; Morgado, J; Sousa, AP; Duarte de Oliveira, S; Custódio, MP; Bruno da Costa, L; Esteves Pena, J

BACKGROUND: Paraneoplastic neurologic syndromes (PNS) pose quite an uncommon neurological complication, affecting less than 1% of patients with breast cancer. Nearly one third of these patients lack detectable onconeural antibodies (ONAs), and improvement in neurologic deficits with concomitant cancer treatments is achieved in less than 30% of cases. CASE PRESENTATION: A 42-year-old, premenopausal woman presen...


Innovative 2D/3D biotextiles for potential bone tissue engineering applications

Almeida, L. R.; Correlo, V. M.; Lisboa, P.; Martins, A. R.; Marques, A. P.; Ribeiro, A. S.; Silva, C.; Sousa, R. A.; Oliveira, A. L.; Reis, R. L.

Bone tissue engineering represents a specialised niche within the biomedical field to which textile technologies can markedly contribute. Textile-based technologies are considered as potential routes for the production of scaffolds for TE applications, as they present superior control over design and reproducibility. This work aims at developing novel 2D/3D textile structures based on different polymeric materi...


Expression patterns of HLA-DR+ or HLA-DR- on CD4+/CD25++/CD127low regulatory T ...

Geraldes, L; Morgado, J; Almeida, A; Todo-Bom, A; Santos, P; Chieira, C; Pais, ML

BACKGROUND: Allergic rhinoconjunctivitis induced by pollen is a highly prevalent chronic inflammatory disease in Europe. Parietariajudaica is a frequent trigger in the Mediterranean area. The function of regulatory T cells (Treg cells) in allergy has recently been investigated, but further data are necessary to better understand their role and to find new strategies to treat allergic diseases such as allergic r...


Application of chitosan in the textile industry to control microbial growth

Tavaria, F. K.; Soares, J.; Oliveira, V.; Silva, R.; Morgado, J.; Malcata, F. X.; Pintado, M. M.


Triplet-State and Singlet Oxygen Formation in Fluorene-Based Alternating Copoly...

Fonseca, S. M.; Pina, J.; Arnaut, L. G.; Melo, J. Seixas de; Burrows, H. D.; Chattopadhyay, N.; Alcácer, L.; Charas, A.; Morgado, J.; Monkman, A. P.

Data are reported on the triplet states of a series of fluorene-based A-alt-B type alternating copolymers based on pulse radiolysis-energy transfer and flash photolysis experiments. From the pulse radiolysis experiments, spectra are given for eight copolymers involving phenylene, thiophene, benzothiadiazole, and oligothienylenevinylene groups. Quantum yields for triplet-state formation (ΦT) have been obtained b...


Influence of Solvent Quality on the Self-Organization of Archetypical Hairy Rod...

Knaapila, M.; Garamus, V. M.; Dias, F. B.; Almásy, L.; Galbrecht, F.; Charas, A.; Morgado, J.; Burrows, H. D.; Scherf, U.; Monkman, A. P.

We report on the nanoscale structure and solvent-induced phase behavior of two, nearly similar π-conjugated hairy-rod polymers, branched side chain poly[9,9-bis(2-ethylhexyl)fluorene-2,7-diyl] (PF2/6) and linear side chain poly[9,9-dioctylfluorene-2,7-diyl] (PFO or PF8), in good and bad (or poor) solventsdeuterated toluene and deuterated methylcyclohexane (MCH)at 20 °C. Small-angle neutron scattering (SANS) mea...


Contact sensitizers downregulate the expression of the chemokine receptors CCR6...

Cruz, M. T.; Gonçalo, M.; Paiva, A.; Morgado, J. M.; Figueiredo, A.; Duarte, C. B.; Lopes, M. C.

Chemokines are involved in the control of dendritic cell (DC) trafficking, which is critical for the immune response, namely in allergic contact dermatitis (ACD). In this work, we investigated by flow cytometry the effect of the contact sensitizers 2,4-dinitrofluorobenzene (DNFB), 1,4-phenylenediamine (PPD) and nickel sulfate (NiSO4), on the surface expression of the chemokine receptors CCR6 and CXCR4 in DC. As...


Welding robots

Pires, J. Norberto; Loureiro, Altino; Godinho, T.; Ferreira, P.; Fernando, B.; Morgado, J.

Using robots in industrial welding operations is common but far from being a streamlined technological process. The problems are with the robots, still in their early design stages and difficult to use and program by regular operators; the welding process, which is complex and not really well known and the human-machine interfaces, which are unnatural and not really working. In this article, these problems are ...


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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia