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MARINE-EXPRESS: taking advantage of high throughput cloning and expression stra...
Groisillier, Agnes; Herve, Cecile; Jeudy, Alexandra; Rebuffet, Etienne; Pluchon, Pierre F.; Chevolot, Yann; Flament, Didier; Geslin, ClaireAbstract Background The production of stable and soluble proteins is one of the most important steps prior to structural and functional studies of biological importance. We investigated the parallel production in a medium throughput strategy of genes coding for proteins from various marine organisms, using protocols that involved recombinatorial cloning, protein expression screening and batch purification. This...
Direitos do Homem, imprensa e poder
Morgado, Isabel SalemaEntendida por muitos como marco civilizacional, coube-me procurar compreender como é percepcionada a Declaração Universal dos Direitos do Homem, na sua dupla projecção: como representação social objectivada no discurso e como enquadramento de uma certa prática política enquanto proposta de exercício do poder para todos os Estados, logo, uma proposta de poder transnacional.
Hormone affinity and fibril formation of piscine transthyretin: the role of the...
Morgado, Isabel; Melo, Eduardo P.; Lundberg, Erik; Estrela, Nídia L.; Sauer-Eriksson, A. Elisabeth; Power, DeborahTransthyretin (TTR) transports thyroid hormones (THs), thyroxine (T4) and triiodothyronine (T3) in the blood of vertebrates. TH-binding sites are highly conserved in vertebrate TTR however, piscine TTR has a longer N-terminus which is thought to influence TH-binding affinity and may influence TTR stability. We produced recombinant wild-type sea bream TTR (sbTTRWT) plus two mutants in which six (sbTTRM6) and twe...
Transthyretin and thyroid hormone transport in fish and the effect of endocrine...
Morgado, Isabel M.Tese dout., Biologia, Universidade do Algarve, 2007
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