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Role of Notch signaling on the differentiation of early lymphoid progenitors ce...

Dissertação para a obtenção do grau de Mestre em Genética Molecular e Biomedicina ; The lymphoid organs, thymus and spleen, are essential for the differentiation of T and B cells, respectively. One of the signaling pathways involved in processes of cell differentiation is the Notch signaling pathway. Work conducted by our group demonstrated that Notch ligands, receptors and target genes are expressed in the th...