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Investigation of human papillomavirus by hybrid capture II in cervical carcinom...
Moreira, M. A. R.; Longatto Filho, Adhemar; Taromaru, Eliane; Queiroz, Geraldo Silva; Jubé, L. F.; Pinto, S. A.; Schmitt, Fernando C.Hybrid capture is an easy and highly sensitive technique for screening population due to its capacity to detect malignant and premalignant lesions of the cervix. To evaluate its ensitivity, we investigated the frequency of high-risk human papillomavirus (HPV) infection and its correlation with glandular malignant lesions, analyzing a total of 113 cases of adenocarcinomas and related lesions. High-risk HPV was ...
P-cadherin expression in glandular lesions of the uterine cervix detected by li...
Longatto Filho, Adhemar; Albergaria, André; Paredes, Joana; Moreira, M. A. R.; Milanezi, Fernanda; Schmitt, Fernando C.Objective: To study P-cadherin aberrant expression as a possible marker for cervical adenocarcinomas in cytological samples. Methods: We studied P-cadherin immunoexpression in liquid-based cervical cytology samples of biopsy-proven cervical lesions. Results: We found a statistically significant correlation between P-cadherin expression and a cytological diagnosis of malignancy, either glandular or squamous (P <...
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