Encontrados 5 documentos, a visualizar página 1 de 1
Alpha-Adrenergic Stimulation Increases Myocardial Distensibility Through PKC Ac...
Sousa, Ana Fontes de; Silva, Carmen Brás; Cardoso, Vera Monteiro; Gonçalves, Nádia Pereira; Conceição, Luísa Lopes; Moreira, Adelino Leite[resumo]
O aumento da distensibilidade miocárdica induzido pela Urocortina 2 é dependent...
Silva, Carmen Brás; Almeida, Mónica; Mendes, Susana; Sousa, Ana Fontes de; Moreira, Adelino Leite[abstract] ; [resumo]
Alpha1-adrenergic stimulation decreases myocardial stiffness: a novel PKC media...
Sousa, Ana Fontes de; Conceição, Luísa Lopes; Silva, Carmen Brás; Moreira, Adelino Leite[abstract] ; [resumo]
Inibidores da enzima de conversão da endotelina e sua aplicação na patologia ca...
Cerdeira, Ana; Silva, Carmen Brás; Moreira, Adelino LeiteEndothelin, a potent vasoconstrictor first described in 1988 by Yanagisawa, is an important regulator of cardiovascular function. Hyperactivation of the endothelin system has been implicated in the pathogenesis of various cardiovascular disorders including myocardial infarction, restenosis, hypertension, heart failure and Chagas cardiopathy. Various attempts have been made to suppress this axis. Although promis...
Efeitos Miocárdicos da Endotelina-1
Silva, Carmen Brás; Moreira, Adelino LeiteEndothelin (ET)-1 was originally identified in 1988 as a vasoconstrictor peptide produced by vascular endothelial cells. It is now known that ET-1 can be produced by vascular and endocardial endothelium and by myocardial cells. Activation of endothelin receptors modulates a wide variety of biological processes including vascular tone, growth and myocardial contractile function. In mammals, ET-1's effects are me...
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